Evidence map›Paper›PMID 35889994›Full record

ArticlePathogens (Basel, Switzerland)2022

Impact of ASFV Detergent Inactivation on Biomarkers in Serum and Saliva Samples.

Lorena Franco-Martínez, Martin Beer, Silvia Martínez-Subiela, Edgar García-Manzanilla, Sandra Blome, Tessa Carrau

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. African Swine Fever Virus: A Review.Life (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Lorena Franco-MartínezInterdisciplinary Laboratory of Clinical Analysis, Interlab-UMU, Regional Campus of International Excellence 'Campus Mare Nostrum', University of Murcia, 30100 Murcia, Spain.ORCID 0000-0003-3375-4274
Martin BeerInstitute of Diagnostic Virology, Friedrich-Loeffler-Institut, Suedufer 10, 17493 Greifswald-Insel Riems, Germany.
Silvia Martínez-SubielaInterdisciplinary Laboratory of Clinical Analysis, Interlab-UMU, Regional Campus of International Excellence 'Campus Mare Nostrum', University of Murcia, 30100 Murcia, Spain.ORCID 0000-0002-1524-1558
Edgar García-ManzanillaMoorepark Animal and Grassland Research Center, Teagasc, Irish Agriculture and Food Development Authority, P61 C996 Cork, Ireland.
Sandra BlomeInstitute of Diagnostic Virology, Friedrich-Loeffler-Institut, Suedufer 10, 17493 Greifswald-Insel Riems, Germany.ORCID 0000-0001-5465-5609
Tessa CarrauInstitute of Diagnostic Virology, Friedrich-Loeffler-Institut, Suedufer 10, 17493 Greifswald-Insel Riems, Germany.ORCID 0000-0002-7021-8684
Friedrich-Loeffler-Institut · DETeagasc - The Irish Agriculture and Food Development Authority · IEUniversidad de Murcia · ES

Funding

European Cooperation in Science and Technology COST Action 15116 ASF-STOPFriedrich-Loeffler-Institut ASF research network HR-0034NexGenerationEU Margarita Salas postdoctoral contract
6 · The paper itself

Abstract

African swine fever (ASF) is a notifiable viral disease of domestic and wild suids. Despite intensive research efforts, the pathogenesis of the disease is still far from being understood. Analysis of biomarkers in different body fluids may supplement traditional pathogenesis studies. As reliable protocols are often established in laboratories with lower biosafety, the reliable inactivation of samples is crucial. The objective of this study was to find a procedure that inactivates the virus while preserving the biomarkers for downstream analyses. To this means, three different inactivation protocols were employed, namely Tergitol-type NP-40 (NP-40), polyoxyethylene-p-t-octylphenol (Triton X-100) and one with 95 °C heating. It could be demonstrated that all samples treated with 0.5% (

Indexed as

African swine feverbiomarkersdetergent treatmentheat treatmentimpact of treatment on biomarkerspathogenesissalivaserumvirus inactivation

Identifiers

PMID35889994
PMCPMC9316758
OpenAlexW4283758468

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.