ArticleNutrients2022
Honeys as Possible Sources of Cholinesterase Inhibitors.
Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Antimicrobial and Antibiofilm Activity of Acacia and Polyfloral Honey: Physicochemical Characterization and Correlation with Antibacterial Efficacy.Foods (Basel, Switzerland) · 2026Article
- Article
- Honey as a Neuroprotective Agent: Molecular Perspectives on Its Role in Alzheimer's Disease.Nutrients · 2025Review
- Exploring the Nutritional Value and Health Benefits of Honey from the Portuguese Protected Area of Montesinho Natural Park.Foods (Basel, Switzerland) · 2025Article
- Chemical Characterization and Biological Properties of Leguminous Honey.Antioxidants (Basel, Switzerland) · 2024Article
- Kombucha Fermentation of Olympus Mountain Tea (Foods (Basel, Switzerland) · 2023Article
- The Potential Use of Honey as a Neuroprotective Agent for the Management of Neurodegenerative Diseases.Nutrients · 2023Review
- Honey and Alzheimer's Disease-Current Understanding and Future Prospects.Antioxidants (Basel, Switzerland) · 2023Review
- In vitro prospective healthy and nutritional benefits of different Citrus monofloral honeys.Scientific reports · 2023Article
- Selectivity Tuning by Natural Deep Eutectic Solvents (NADESs) for Extraction of Bioactive Compounds fromMolecules (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterised by low levels of the neurotransmitter (acetylcholine), oxidative stress, and inflammation of the central nervous system. The only currently available form of treatment entails the administration of AChE/BChE (acetylcholinesterase/butyrylcholinesterase) inhibitors to patients diagnosed with the disease. However, AD prevention is possible by administering the correct inhibitors with food. The aim of this study was to examine 19 types of honey in terms of their contents of cholinesterase inhibitors. The inhibition of AChE and BChE relative to the respective honey samples was evaluated using Ellman's colorimetric method, including the "false-positive" effect. The highest potential for AChE inhibition was observed in the case of thyme honey (21.17% inhibition), while goldenrod honey showed the highest capacity for BChE inhibition (33.89%). Our study showed that honeys may provide a rich source of cholinesterase inhibitors and, in this way, play a significant role in AD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.