ReviewNutrients2022
Iron Deficiency Anemia: Efficacy and Limitations of Nutritional and Comprehensive Mitigation Strategies.
Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06521879 (Improved Gastrointestinal Tolerance and Iron Status Via Probiotic Use in Iron Deficiency Anemia Patients Initiating Oral Iron Replacement), which is not on this map. Cited by 93 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Improved Gastrointestinal Tolerance and Iron Status Via Probiotic Use in Iron Deficiency Anemia Patients Initiating Oral Iron Replacement
Who cites it
93 citing papers in PubMed, 6 syntheses or guidelines pooled it, 223 citations in OpenAlex.
- Effect of different Iron-Folic acid (IFA) formulations, doses, and frequencies on pregnancy and neonatal outcomes compared to multiple micronutrients (MMN) among pregnant women: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2025Pooled it
- Prevalence and associated factors of anemia among newborns in Africa: a systematic review and meta-analysis.BMC pediatrics · 2025Pooled it
- Effect of Interventions on Iron-Deficiency Anemia Among School-Going Children in India: A Systematic Review and Network Meta-Analysis.Journal of research in health sciences · 2025Pooled it
- Pooled it
- Relationship between Iron Deficiency and Thyroid Function: A Systematic Review and Meta-Analysis.Nutrients · 2023Pooled it
- Prevalence of Anemia among Children and Adolescents of Bangladesh: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023Pooled it
- Improved gastrointestinal tolerance and iron status via probiotic use in iron deficiency anaemia patients initiating oral iron replacement: a randomised controlled trial.The British journal of nutrition · 2024Trial
- The hidden vulnerability: heavy and persistent burden of dietary iron deficiency among women and children in China, India and globally based on the global burden of disease 2021.Annals of medicine · 2026Article
- Iron Supplementation and Neurodevelopmental Outcomes in Infancy and Early Childhood: A Review.Children (Basel, Switzerland) · 2026Review
- Multielement Composition and in Vitro Bioaccessibility in Brazilian Edible Floral Supplement Capsules Containing Dandelion and Hibiscus.Biological trace element research · 2026Article
- Increasing utilisation of intravenous iron among Australian women of reproductive age, 2013-2024: an Australian population-based study.Internal medicine journal · 2026Observational
- Biofortification ofFood science & nutrition · 2026Article
- Structure-Function Relationships in Polysaccharide-Iron Complexes: Molecular Characterization, Acid-Stress Release Stability, and Gastrointestinal Tolerability.Pharmaceutics · 2026Article
- Article
- Wheat landraces and microbiome endophytic phytases: In vitro/in silico study for iron bioavailability.Food chemistry. Molecular sciences · 2026Article
- Article
- Impact of fortified food distributed through Anganwadi centers in the prevention of anemia among children in Andhra Pradesh.Journal of family medicine and primary care · 2026Article
- Sex and gender differences in responses to antianemic therapies: biological mechanisms and clinical implications.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Iron deficiency anemia perturbs erythrocyte morphology and may promote eryptosis.International journal of hematology · 2026Article
- Essential Trace Elements in Edible Plants: Balancing Nutritional Benefits and Potential Health Risks.Journal of agricultural and food chemistry · 2026Article
33 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iron deficiency anemia (IDA) has reached epidemic proportions in developing countries and has become a major global public health problem, affecting mainly 0-5-year-old children and young women of childbearing age, especially during pregnancy. Iron deficiency can lead to life-threatening loss of red blood cells, muscle function, and energy production. Therefore, the pathogenic features associated with IDA are weakness and impaired growth, motor, and cognitive performance. IDA affects the well-being of the young generation and the economic advancement of developing countries, such as India. The imbalance between iron intake/absorption/storage and iron utilization/loss culminates into IDA. However, numerous strategic programs aimed to increase iron intake have shown that improvement of iron intake alone has not been sufficient to mitigate IDA. Emerging critical risk factors for IDA include a composition of cultural diets, infections, genetics, inflammatory conditions, metabolic diseases, dysbiosis, and socioeconomic parameters. In this review, we discuss numerous IDA mitigation programs in India and their limitations. The new multifactorial mechanism of IDA pathogenesis opens perspectives for the improvement of mitigation programs and relief of IDA in India and worldwide.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.