Evidence map›Paper›PMID 35889897›Full record

ArticleNutrients2022

Magnesium Status and Ca/Mg Ratios in a Series of Children and Adolescents with Chronic Diseases.

Marlene Fabiola Escobedo-Monge, Enrique Barrado, Joaquín Parodi-Román, María Antonieta Escobedo-Monge, María Carmen Torres-Hinojal, José Manuel Marugán-Miguelsanz

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Marlene Fabiola Escobedo-MongeFaculty of Medicine, Valladolid University, Avenida Ramón y Cajal, 7, 47005 Valladolid, Spain.ORCID 0000-0002-1295-3752
Enrique BarradoDepartment of Analytical Chemistry, Science Faculty, Campus Miguel Delibes, University of Valladolid, Calle Paseo de Belén, 7, 47011 Valladolid, Spain.
Joaquín Parodi-RománScience Faculty, Cadiz University, Paseo de Carlos III, 28, 11003 Cádiz, Spain.
María Antonieta Escobedo-MongeDepartment of Chemistry, Science Faculty, University of Burgos, Plaza Misael Bañuelos sn, 09001 Burgos, Spain.ORCID 0000-0001-6318-7333
María Carmen Torres-HinojalFaculty of Medicine, Valladolid University, Avenida Ramón y Cajal, 7, 47005 Valladolid, Spain.
José Manuel Marugán-MiguelsanzDepartment of Pediatrics, Faculty of Medicine, Valladolid University, Avenida Ramón y Cajal, 7, 47005 Valladolid, Spain.
Universidad de Valladolid · ESUniversidad de Cádiz · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnesium (Mg) is an essential divalent cation involved in various enzymatic reactions that regulate vital biological functions. The main goal was to evaluate Mg status and its association with nutritional indicators in 78 children and adolescents with chronic diseases. We assessed anthropometric, biochemical, diet, body composition, and bone densitometry valuations. Serum Mg and Ca levels were determined using the standardized method and diet calcium (Ca) and Mg consumption by a prospective 72 h diet survey. Mean serum Ca (9.9 mg/dL), Mg (2.08 mg/dL) dietary Ca (102% DRI: Dietary Reference Intake), and Mg intake (105% DRI) were normal. A total of 45% had hypomagnesemia, 12% had hypermagnesemia, and 26% and 24% had inadequate and high Mg intake, respectively. Only 6% of patients had poor Mg intake and hypomagnesemia, and 54% and 90% of our series had an elevated serum Ca/Mg ratio > 4.70 (mean 4.79) and a low Ca/Mg intake ratio < 1.70 (mean 1.06), respectively. Both Ca/Mg ratios were linked with the risk of developing other chronic conditions such as cardiovascular disease, type 2 diabetes, syndrome metabolic, and even several cancers. Therefore, 79% of children and adolescents with chronic diseases were at elevated risk of having abnormal Mg status and developing other chronic illnesses.

Indexed as

Diabetes Mellitus, Type 2Magnesium DeficiencyAdolescentCalciumChildChronic DiseaseHumansMagnesiumProspective StudiesCalciumMagnesiumdietary magnesium intakehypercalcemiahypermagnesemiahypomagnesemiasubclinical magnesium deficiency

Identifiers

PMID35889897
PMCPMC9315923
OpenAlexW4285803083

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.