Evidence map›Paper›PMID 35889880›Full record

ArticleNutrients2022

Assessment of SARS-CoV-2 Infection According to Previous Metabolic Status and Its Association with Mortality and Post-Acute COVID-19.

Alejandro de Arriba Fernández, José Luis Alonso Bilbao, Alberto Espiñeira Francés, Antonio Cabeza Mora, Ángela Gutiérrez Pérez, Miguel Ángel Díaz Barreiros, Lluís Serra Majem

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 4 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 4 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Abnormal glucose metabolism in virus associated sepsis.Frontiers in cellular and infection microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alejandro de Arriba FernándezResearch Institute of Biomedical and Health Sciences, University of Las Palmas de Gran Canaria, 35001 Las Palmas de Gran Canaria, Spain.ORCID 0000-0001-5493-8780
José Luis Alonso BilbaoGerencia de Atención Primaria de Gran Canaria, 35006 Las Palmas de Gran Canaria, Spain.
Alberto Espiñeira FrancésGerencia de Atención Primaria de Gran Canaria, 35006 Las Palmas de Gran Canaria, Spain.
Antonio Cabeza MoraGerencia de Atención Primaria de Gran Canaria, 35006 Las Palmas de Gran Canaria, Spain.
Ángela Gutiérrez PérezGerencia de Atención Primaria de Gran Canaria, 35006 Las Palmas de Gran Canaria, Spain.ORCID 0000-0002-3382-5573
Miguel Ángel Díaz BarreirosGerencia de Atención Primaria de Gran Canaria, 35006 Las Palmas de Gran Canaria, Spain.
Lluís Serra MajemResearch Institute of Biomedical and Health Sciences, University of Las Palmas de Gran Canaria, 35001 Las Palmas de Gran Canaria, Spain.ORCID 0000-0002-9658-9061
Gobierno de Canarias · ESUniversidad de Las Palmas de Gran Canaria · ES

Funding

Fundación DISA A38445839Fundación Española de Calidad Asistencial G74295718
6 · The paper itself

Abstract

Background. SARS-CoV-2 infection was analyzed according to previous metabolic status and its association with mortality and post-acute COVID-19. Methods. A population-based observational retrospective study was conducted on a cohort of 110,726 patients aged 12 years or more who were diagnosed with COVID-19 infection between June 1st, 2021, and 28 February 2022 on the island of Gran Canaria, Spain. Results. In the 347 patients who died, the combination of advanced age, male sex, cancer, immunosuppressive therapy, coronary heart disease, elevated total cholesterol and reduced high-density lipoprotein cholesterol (HDL-C) was strongly predictive of mortality (p < 0.05). In the 555 patients who developed post-acute COVID-19, the persistence of symptoms was most frequent in women, older subjects and patients with obstructive sleep apnea syndrome, asthma, elevated fasting glucose levels or elevated total cholesterol (p < 0.05). A complete vaccination schedule was associated with lower mortality (incidence rate ratio (IRR) 0.5, 95%CI 0.39−0.64; p < 0.05) and post-acute COVID-19 (IRR 0.37, 95%CI 0.31−0.44; p < 0.05). Conclusions. Elevated HDL-C and elevated total cholesterol were significantly associated with COVID-19 mortality. Elevated fasting glucose levels and elevated total cholesterol were risk factors for the development of post-acute COVID-19.

Indexed as

COVID-19CholesterolCholesterol, HDLFemaleGlucoseHumansMaleRetrospective StudiesSARS-CoV-2CholesterolCholesterol, HDLGlucoseblood lipidscoronavirus disease 2019fasting glucose levelshigh-density lipoprotein cholesterolmortalitypost-acute COVID-19risk factorsSARS-CoV-2total cholesterol

Identifiers

PMID35889880
PMCPMC9325256
OpenAlexW4285732086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.