Evidence map›Paper›PMID 35889875›Full record

ArticleNutrients2022

Comparison of Five Oxidative Stress Biomarkers in Vegans and Omnivores from Germany and Finland.

Stefan Dietrich, Anna-Liisa Elorinne, Nick Bergau, Klaus Abraham, Tilman Grune, Juha Laakso, Daniela Weber, Cornelia Weikert, Bernhard H Monien

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Stefan DietrichDepartment of Food Safety, German Federal Institute for Risk Assessment, 10589 Berlin, Germany.
Anna-Liisa ElorinneSchool of Applied Educational Science and Teacher Education, University of Eastern Finland, 80101 Joensuu, Finland.ORCID 0000-0001-6138-2338
Nick BergauDepartment of Food Safety, German Federal Institute for Risk Assessment, 10589 Berlin, Germany.
Klaus AbrahamDepartment of Food Safety, German Federal Institute for Risk Assessment, 10589 Berlin, Germany.ORCID 0000-0003-1895-9909
Tilman GruneDepartment of Molecular Toxicology, German Institute of Human Nutrition, Potsdam-Rehbruecke (DIfE), 14558 Nuthetal, Germany.ORCID 0000-0003-4775-9973
Juha LaaksoClinical Research Institute HUCH, 00280 Helsinki, Finland.
Daniela WeberDepartment of Molecular Toxicology, German Institute of Human Nutrition, Potsdam-Rehbruecke (DIfE), 14558 Nuthetal, Germany.ORCID 0000-0002-2054-6233
Cornelia WeikertDepartment of Food Safety, German Federal Institute for Risk Assessment, 10589 Berlin, Germany.
Bernhard H MonienDepartment of Food Safety, German Federal Institute for Risk Assessment, 10589 Berlin, Germany.
Federal Institute for Risk Assessment · DEGerman Institute of Human Nutrition · DEUniversity of Eastern Finland · FI

Funding

Juho Vainio Foundation
6 · The paper itself

Abstract

When the amount of reactive oxygen species produced by human metabolism cannot be balanced by antioxidants, this phenomenon is commonly referred to as oxidative stress. It is hypothesised that diets with high amounts of plant food products may have a beneficial impact on oxidative stress status. However, few studies have examined whether a vegan diet is associated with lower oxidative stress compared to an omnivorous diet. The present cross-sectional study aimed to compare the levels of five oxidative stress biomarkers in vegans and omnivores. Data of 36 vegans and 36 omnivores from Germany and of 21 vegans and 18 omnivores from Finland were analysed. HPLC coupled with mass spectrometry or fluorescence detection and ELISA methods were used to measure the oxidative stress biomarkers malondialdehyde (MDA), protein carbonyls and 3-nitrotyrosine in plasma and 8-hydroxy-2'-deoxyguanosine (8-OHdG) and 8-iso-prostaglandin F2α (8-iso-PGF2α) in 24 h urine. Analyses of variance and covariance, considering potential confounders, were used. Vegans and omnivores showed no differences in MDA and protein carbonyl concentrations. In Finnish but not in German vegans, the concentrations of 3-nitrotyrosine were lower compared to those in omnivores (

Indexed as

Diet, VeganVegansBiomarkersCross-Sectional StudiesDiet, VegetarianFemaleFinlandGermanyHumansMaleOxidative StressBiomarkers3-nitrotyrosine8-hydroxy-2′-deoxyguanosine8-iso-prostaglandin F2αmalondialdehydeomnivorous dietoxidative stressprotein carbonylsvegan diet

Identifiers

PMID35889875
PMCPMC9323774
OpenAlexW4285732761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.