Evidence map›Paper›PMID 35889834›Full record

Trial reportNutrients2022

Evaluation of the Effectiveness of Fermented Soybean-Lettuce Powder for Improving Menopausal Symptoms.

A Lum Han, Hee Kyung Lee, Hyun Soo Chon, Hyun Ock Pae, Min Sun Kim, Yong Il Shin, Sooah Kim

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

A Lum HanDepartment of Family Medicine, Wonkwang University Hospital, Iksan 54538, Korea.
Hee Kyung LeeDepartment of Family Medicine, Wonkwang University Hospital, Iksan 54538, Korea.
Hyun Soo ChonHumanEnos LLC., Wanju 55347, Korea.
Hyun Ock PaeDepartment of Microbiology and Immunology, School of Medicine, Iksan 54538, Korea.
Min Sun KimCenter for Nitric Oxide Metabolite at Wonkwang University, Iksan 54538, Korea.
Yong Il ShinDepartment of Rehabilitation Medicine, Pusan National University School of Medicine, Busan 50612, Korea.
Sooah KimDepartment of Environment Science & Biotechnology, Jeonju University, Jeonju 55069, Korea.
Wonkwang University · KRJeonju University · KRPusan National University · KR

Funding

Jeonbuk Research & Development Program RA2021-02-C3-04
6 · The paper itself

Abstract

Menopause syndrome causes a decline in the quality of life of postmenopausal women. Hormone therapy is recommended for the treatment of menopausal syndromes. However, it has several side effects. Soybean has been safely used to relieve the symptoms of menopause. Lettuce has antidiabetic and anti-inflammatory effects and improves sleep quality. Natural nitric oxide metabolites are produced through fermentation, which increases the effectiveness of the functional substances. This study assessed the alleviation of menopausal syndrome symptoms by natural nitric oxide-containing soybean lettuce extract using the Kupperman index. This study included adult women with menopausal syndrome and a Kupperman index of ≥15. After a four-week study with 40 participants, the final analysis included 39 participants in the experimental group (

Indexed as

Fermented FoodsGlycine maxAdultCholesterol, HDLFemaleHot FlashesHumansLactucaMenopauseNitric OxidePlant ExtractsPowdersQuality of LifeCholesterol, HDLNitric OxidePlant ExtractsPowdersfermentationkupperman indexlettucemenopausal syndromenitric oxidesoybean

Identifiers

PMID35889834
PMCPMC9317582
OpenAlexW4285392411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.