Evidence map›Paper›PMID 35889699›Full record

ReviewNanomaterials (Basel, Switzerland)2022

Ultrasmall-in-Nano: Why Size Matters.

Ryan D Mellor, Ijeoma F Uchegbu

Open access · goldAbstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Clustered, SERS-Active, Ultrasmall AuNPs for Photothermal Therapy.International journal of nanomedicine · 2025
    Article
  9. Strain-SpecificInternational journal of nanomedicine · 2025
    Article
  10. Nano-structured strategies in combatting neurodegeneration.Frontiers in bioengineering and biotechnology · 2025
    Review
  11. Review
  12. Bornite (CuPhotoacoustics · 2024
    Article
  13. CuACS applied nano materials · 2024
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ryan D MellorSchool of Pharmacy, University College London (UCL), 29-39 Brunswick Square, London WC1N 1AX, UK.ORCID 0000-0002-0677-5603
Ijeoma F UchegbuSchool of Pharmacy, University College London (UCL), 29-39 Brunswick Square, London WC1N 1AX, UK.ORCID 0000-0001-9586-6867
University College London · GB

Funding

Engineering and Physical Sciences Research Council EP/R020965/1
6 · The paper itself

Abstract

Gold nanoparticles (AuNPs) are continuing to gain popularity in the field of nanotechnology. New methods are continuously being developed to tune the particles' physicochemical properties, resulting in control over their biological fate and applicability to in vivo diagnostics and therapy. This review focuses on the effects of varying particle size on optical properties, opsonization, cellular internalization, renal clearance, biodistribution, tumor accumulation, and toxicity. We review the common methods of synthesizing ultrasmall AuNPs, as well as the emerging constructs termed ultrasmall-in-nano-an approach which promises to provide the desirable properties from both ends of the AuNP size range. We review the various applications and outcomes of ultrasmall-in-nano constructs in vitro and in vivo.

Indexed as

biodistributionclearancegold nanoparticlestoxicitytumor accumulationultrasmall-in-nano

Identifiers

PMID35889699
PMCPMC9317835
OpenAlexW4286219820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.