ArticleNanomaterials (Basel, Switzerland)2022
Optimization of Technological Parameters of the Process of Forming Therapeutic Biopolymer Nanofilled Films.
Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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Who cites it
3 citing papers in PubMed.
- The Study Influence Analysis of the Mathematical Model Choice for Describing Polymer Behavior.Polymers · 2023Article
- Optical and Mechanical Properties of Layered Infrared Interference Filters.Sensors (Basel, Switzerland) · 2022Article
- Multiclass Level-Set Segmentation of Rust and Coating Damages in Images of Metal Structures.Sensors (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The prospects of using biopolymer nano-containing films for wound healing were substantiated. The main components of biopolymer composites are gelatin, polyvinyl alcohol, glycerin, lactic acid, distilled water, and zinc oxide (ZnO) nanoparticles (NPs). Biopolymer composites were produced according to various technological parameters using a mould with a chrome coating. The therapeutic properties of biopolymer films were evaluated by measuring the diameter of the protective effect. Physico-mechanical properties were studied: elasticity, vapour permeability, degradation time, and swelling. To study the influence of technological parameters of the formation process of therapeutic biopolymer nanofilled films on their therapeutic and physico-mechanical properties, the planning of the experiment was used. According to the results of the experiments, mathematical models of the second-order were built. The optimal values of technological parameters of the process are determined, which provide biopolymer nanofilled films with maximum healing ability (diameter of protective action) and sufficiently high physical and mechanical properties: elasticity, vapour permeability, degradation time and swelling. The research results showed that the healing properties of biopolymer films mainly depend on the content of ZnO NPs. Degradation of these biopolymer films provides dosed drug delivery to the affected area. The products of destruction are carbon dioxide, water, and a small amount of ZnO in the bound state, which indicates the environmental safety of the developed biopolymer film.
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Registered trials
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