Evidence map›Paper›PMID 35889493›Full record

ArticleMolecules (Basel, Switzerland)2022

Synthesis and Biological Activity Screening of Newly Synthesized Trimethoxyphenyl-Based Analogues as Potential Anticancer Agents.

Tarfah Al-Warhi, Matokah Abualnaja, Ola A Abu Ali, Fayez Althobaiti, Fahad Alharthi, Fahmy G Elsaid, Ali A Shati, Eman Fayad, Doaa Elghareeb, Ali H Abu Almaaty and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. New Heterocyclic Compounds from Oxazol-5(4Molecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tarfah Al-WarhiDepartment of Chemistry, College of Science, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia.
Matokah AbualnajaDepartment of Chemistry, Faculty of Applied Science, Umm Al-Qura University, Makkah Al Mukarrama 24381, Saudi Arabia.
Ola A Abu AliDepartment of Chemistry, College of Science, Taif University, Taif 21944, Saudi Arabia.
Fayez AlthobaitiDepartment of Biotechnology, Faculty of Sciences, Taif University, Taif 21944, Saudi Arabia.
Fahad AlharthiDepartment of Biology, College of Science, Taif University, Taif 21944, Saudi Arabia.
Fahmy G ElsaidBiology Department, Science College, King Khalid University, Abha 61421, Saudi Arabia.ORCID 0000-0002-7754-2524
Ali A ShatiBiology Department, Science College, King Khalid University, Abha 61421, Saudi Arabia.
Eman FayadDepartment of Biotechnology, Faculty of Sciences, Taif University, Taif 21944, Saudi Arabia.ORCID 0000-0003-2916-0254
Doaa ElghareebDepartment of Biology, Jumum College University, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
Ali H Abu AlmaatyZoology Department, Faculty of Science, Port Said University, Port Said 42526, Egypt.ORCID 0000-0001-9056-0228
Islam ZakiPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Port Said University, Port Said 42526, Egypt.ORCID 0000-0002-2026-7373

Funding

Princess Nourah bint Abdulrahman University Researchers Supporting Project number (PNURSP2022R25), Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia PNURSP2022R25
6 · The paper itself

Abstract

A group of novel trimethoxyphenyl (TMP)-based analogues were synthesized by varying the azalactone ring of 2-(3,4-dimethoxyphenyl)-4-(3,4,5-trimethoxybenzylidene)oxazolone

Indexed as

Antineoplastic AgentsApoptosisCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorMolecular StructureStructure-Activity RelationshipTubulinTubulin ModulatorsAntineoplastic AgentsTubulinTubulin Modulatorsapoptosiscell cycle analysiscytotoxicitydiamideimidazoloneoxazolonetriazinonetubulin

Identifiers

PMID35889493
PMCPMC9322052

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.