Evidence map›Paper›PMID 35889462›Full record

ArticleMolecules (Basel, Switzerland)2022

Antifungal Effects and Active Components of Ligusticum chuanxiong

Huabao Chen, Yingchun Zhao, Guangwei Qin, Yan Bi, Guizhou Yue, Min Zhang, Xiaoli Chang, Xiaoyan Qiu, Liya Luo, Chunping Yang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Foods (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Journal of pain research · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Huabao ChenCollege of Agronomy, Sichuan Agricultural University, Chengdu 611130, China.
Yingchun ZhaoCollege of Agronomy, Sichuan Agricultural University, Chengdu 611130, China.
Guangwei QinCollege of Agronomy, Sichuan Agricultural University, Chengdu 611130, China.
Yan BiCollege of Agronomy, Sichuan Agricultural University, Chengdu 611130, China.
Guizhou YueCollege of Science, Sichuan Agricultural University, Ya'an 625000, China.ORCID 0000-0001-7811-0531
Min ZhangCollege of Agronomy, Sichuan Agricultural University, Chengdu 611130, China.
Xiaoli ChangCollege of Agronomy, Sichuan Agricultural University, Chengdu 611130, China.
Xiaoyan QiuCollege of Agronomy, Sichuan Agricultural University, Chengdu 611130, China.
Liya LuoCollege of Agronomy, Sichuan Agricultural University, Chengdu 611130, China.
Chunping YangCollege of Agronomy, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0003-3433-7835
Sichuan Agricultural University · CN

Funding

Sichuan Provincial Department of Education No. 2017NZDZX0003
6 · The paper itself

Abstract

The separation of chemical components from wild plants to develop new pesticides is a hot topic in current research. To evaluate the antimicrobial effects of metabolites of Ligusticum chuanxiong (CX), we systematically studied the antimicrobial activity of extracts of CX, and the active compounds were isolated, purified and structurally identified. The results of toxicity measurement showed that the extracts of CX had good biological activities against Botrytis cinerea, Sclerotinia sclerotiorum, Alternaria alternata and Pythium aphanidermatum, and the value of EC50 were 130.95, 242.36, 332.73 and 307.29 mg/L, respectively. The results of in vivo determination showed that under the concentration of 1000 mg/L, the control effect of CX extract on Blumeria graminis was more than 40%, and the control effect on Botrytis cinerea was 100%. The antifungal active components of CX were identified as Senkyunolide A and Ligustilide by mass spectrometry and nuclear magnetic resonance. The MIC (minimum inhibitory concentration) value of Senkyunolide A and Ligustilide against Fusarium graminearum were 7.81 and 62.25 mg/L, respectively. As a new botanical fungicide with a brightly exploitative prospect, CX extract has potential research value in the prevention and control of plant diseases.

Indexed as

Drugs, Chinese HerbalLigusticumAntifungal AgentsBotrytisAntifungal AgentsDrugs, Chinese Herbalantifungal activityLigusticum chuanxiongLigustilideSenkyunolide A

Identifiers

PMID35889462
PMCPMC9320862
OpenAlexW4285795906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.