Evidence map›Paper›PMID 35889350›Full record

ReviewMolecules (Basel, Switzerland)2022

Doxorubicin-Based Hybrid Compounds as Potential Anticancer Agents: A Review.

Sijongesonke Peter, Sibusiso Alven, Rejoice Bethusile Maseko, Blessing Atim Aderibigbe

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 111 citations in OpenAlex.

  1. Pharmaceuticals (Basel, Switzerland) · 2026
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  6. Review
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  11. Phosphatidylcholine-derived carriers facilitate brain tumor delivery and enhance glioblastoma therapy.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Article
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  15. Article
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  18. Design of New Daunorubicin Derivatives with High Cytotoxic Potential.International journal of molecular sciences · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sijongesonke PeterDepartment of Chemistry, University of Fort Hare, Alice 5700, South Africa.ORCID 0000-0002-6935-905X
Sibusiso AlvenDepartment of Chemistry, University of Fort Hare, Alice 5700, South Africa.ORCID 0000-0001-7100-4007
Rejoice Bethusile MasekoDepartment of Chemistry, School of Science and Technology, Sefako Makgatho Health Sciences University, Ga-Rankuwa 0208, South Africa.
Blessing Atim AderibigbeDepartment of Chemistry, University of Fort Hare, Alice 5700, South Africa.
University of Fort Hare · ZASefako Makgatho Health Sciences University · ZA

Funding

South African Medical Research Council SAMRC
6 · The paper itself

Abstract

The scarcity of novel and effective therapeutics for the treatment of cancer is a pressing and alarming issue that needs to be prioritized. The number of cancer cases and deaths are increasing at a rapid rate worldwide. Doxorubicin, an anticancer agent, is currently used to treat several types of cancer. It disrupts myriad processes such as histone eviction, ceramide overproduction, DNA-adduct formation, reactive oxygen species generation, Ca

Indexed as

Antineoplastic AgentsDoxorubicinDNA DamageHistonesHumansAntineoplastic AgentsDoxorubicinHistonescancerchemotherapeutic drugsdoxorubicindrug resistancedrug toxicityhybrid compounds

Identifiers

PMID35889350
PMCPMC9318127
OpenAlexW4285393804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.