Evidence map›Paper›PMID 35889270›Full record

ArticleMolecules (Basel, Switzerland)2022

Supported Gold Nanoparticle-Catalyzed Selective Reduction of Multifunctional, Aromatic Nitro Precursors into Amines and Synthesis of 3,4-Dihydroquinoxalin-2-Ones.

Domna Iordanidou, Michael G Kallitsakis, Marina A Tzani, Dimitris I Ioannou, Tryfon Zarganes-Tzitzikas, Constantinos G Neochoritis, Alexander Dömling, Michael A Terzidis, Ioannis N Lykakis

Abstract read
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In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Domna IordanidouDepartment of Chemistry, Aristotle University of Thessaloniki, University Campus, 54124 Thessaloniki, Greece.
Michael G KallitsakisDepartment of Chemistry, Aristotle University of Thessaloniki, University Campus, 54124 Thessaloniki, Greece.
Marina A TzaniDepartment of Chemistry, Aristotle University of Thessaloniki, University Campus, 54124 Thessaloniki, Greece.ORCID 0000-0003-0878-1529
Dimitris I IoannouDepartment of Chemistry, Aristotle University of Thessaloniki, University Campus, 54124 Thessaloniki, Greece.ORCID 0000-0002-8804-1610
Tryfon Zarganes-TzitzikasAlzheimer's Research UK Oxford Drug Discovery Institute, University of Oxford, Oxford OX3 7FZ, UK.
Constantinos G NeochoritisDepartment of Chemistry, University of Crete, Voutes Heraklion, 70013 Heraklion, Greece.ORCID 0000-0001-5098-5504
Alexander DömlingDepartment of Pharmacy, University of Groningen, A. Deusinglaan 1, 9700 AV Groningen, The Netherlands.ORCID 0000-0002-9923-8873
Michael A TerzidisDepartment of Nutritional Sciences and Dietetics, International Hellenic University, Sindos Campus, 57400 Thessaloniki, Greece.ORCID 0000-0001-8835-6623
Ioannis N LykakisDepartment of Chemistry, Aristotle University of Thessaloniki, University Campus, 54124 Thessaloniki, Greece.ORCID 0000-0001-8165-5604

Funding

Hellenic Foundation for Research and Innovation and General Secretariat for Research and Innovation 776
6 · The paper itself

Abstract

The synthesis of 3,4-dihydroquinoxalin-2-ones via the selective reduction of aromatic, multifunctional nitro precursors catalyzed by supported gold nanoparticles is reported. The reaction proceeds through the in situ formation of the corresponding amines under heterogeneous transfer hydrogenation of the initial nitro compounds catalyzed by the commercially available Au/TiO

Indexed as

GoldMetal NanoparticlesAminesCatalysisHydrogenationAminesGold3,4-dihydroquinoxalin-2-onesaromatic aminescatalysisgold nanoparticlesheterocyclesnitro compoundsreduction

Identifiers

PMID35889270
PMCPMC9323044

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.