Evidence map›Paper›PMID 35889198›Full record

ArticleMolecules (Basel, Switzerland)2022

Membrane Permeabilization and Antimicrobial Activity of Recombinant Defensin-d2 and Actifensin against Multidrug-Resistant

Ifeoluwa D Gbala, Rosaline W Macharia, Joel L Bargul, Gabriel Magoma

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. The Contribution of Human Antimicrobial Peptides to Fungi.International journal of molecular sciences · 2025
    Review
  9. Article
  10. Review
  11. Anti-Frontiers in microbiology · 2023
    Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ifeoluwa D GbalaMolecular Biology and Biotechnology, Institute for Basic Sciences, Technology and Innovation, Pan African University, Nairobi P.O. Box 62000-00200, Kenya.
Rosaline W MachariaCentre for Biotechnology and Bioinformatics, University of Nairobi, Nairobi P.O. Box 30197-00100, Kenya.
Joel L BargulDepartment of Biochemistry, Jomo Kenyatta University of Agriculture and Technology, Nairobi P.O. Box 62000-00200, Kenya.
Gabriel MagomaMolecular Biology and Biotechnology, Institute for Basic Sciences, Technology and Innovation, Pan African University, Nairobi P.O. Box 62000-00200, Kenya.
Jomo Kenyatta University of Agriculture and Technology · KEUniversity of Nairobi · KE

Funding

African Union Pan African University Scholarship
6 · The paper itself

Abstract

Antimicrobial resistance requires urgent efforts towards the discovery of active antimicrobials, and the development of strategies to sustainably produce them. Defensin and defensin-like antimicrobial peptides (AMPs) are increasingly gaining pharmacological interest because of their potency against pathogens. In this study, we expressed two AMPs: defensin-d2 derived from spinach, and defensin-like actifensin from

Indexed as

Anti-Infective AgentsCandida albicansDefensinsPseudomonas aeruginosaAnti-Bacterial AgentsDrug Resistance, BacterialEscherichia coliMicrobial Sensitivity TestsPeptidesRecombinant ProteinsAnti-Bacterial AgentsAnti-Infective AgentsDefensinsPeptidesRecombinant Proteinsactifensinantimicrobial peptidesmultidrug-resistantrecombinantspinach defensin

Identifiers

PMID35889198
PMCPMC9317813
OpenAlexW4283824124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.