Evidence map›Paper›PMID 35889137›Full record

ArticleMicroorganisms2022

Jean Pierre Musabyimana, Ute Distler, Juliane Sassmannshausen, Christina Berks, Janice Manti, Sandra Bennink, Lea Blaschke, Paul-Christian Burda, Ansgar Flammersfeld, Stefan Tenzer and 2 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Integrative genomics ofbioRxiv : the preprint server for biology · 2026
    Article
  2. TheInternational journal of molecular sciences · 2025
    Article
  3. Review
  4. ThemSphere · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Jean Pierre MusabyimanaDivision of Cellular and Applied Infection Biology, Institute of Zoology, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.
Ute DistlerProteomics Core Facility, Institute of Immunology, University Medical Center of the Johannes-Gutenberg University Mainz, Langenbeckstraße 1, 55131 Mainz, Germany.ORCID 0000-0002-8031-6384
Juliane SassmannshausenDivision of Cellular and Applied Infection Biology, Institute of Zoology, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.
Christina BerksDivision of Cellular and Applied Infection Biology, Institute of Zoology, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.
Janice MantiDivision of Cellular and Applied Infection Biology, Institute of Zoology, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.
Sandra BenninkDivision of Cellular and Applied Infection Biology, Institute of Zoology, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.
Lea BlaschkeDivision of Cellular and Applied Infection Biology, Institute of Zoology, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.ORCID 0000-0003-1006-2793
Paul-Christian BurdaCentre for Structural Systems Biology (CSSB) c/o DESY, Bernhard Nocht Institute, University of Hamburg, Notkestraße 85, Building 15, 22607 Hamburg, Germany.
Ansgar FlammersfeldDivision of Cellular and Applied Infection Biology, Institute of Zoology, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.
Stefan TenzerProteomics Core Facility, Institute of Immunology, University Medical Center of the Johannes-Gutenberg University Mainz, Langenbeckstraße 1, 55131 Mainz, Germany.ORCID 0000-0003-3034-0017
Che Julius NgwaDivision of Cellular and Applied Infection Biology, Institute of Zoology, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.
Gabriele PradelDivision of Cellular and Applied Infection Biology, Institute of Zoology, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany.ORCID 0000-0003-2264-5558
RWTH Aachen University · DEJohannes Gutenberg University Mainz · DEUniversität Hamburg · DE

Funding

Deutsche Forschungsgemeinschaft PR905/19-1 (SPP 2225); TE599/9-1 (SPP 2225); PR905/20-1; NG170/1-1Deutscher Akademischer Austauschdienst PhD Stipend JPM
6 · The paper itself

Abstract

S-adenosylmethionine synthetase (SAMS) is a key enzyme for the synthesis of the lone methyl donor S-adenosyl methionine (SAM), which is involved in transmethylation reactions and hence required for cellular processes such as DNA, RNA, and histone methylation, but also polyamine biosynthesis and proteostasis. In the human malaria parasite

Indexed as

drug targethistone methylationinteractomemalariaPlasmodium falciparumpolyamine biosynthesisproteasomeSAMSAMStranscriptional regulation

Identifiers

PMID35889137
PMCPMC9320499
OpenAlexW4285594963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.