Evidence map›Paper›PMID 35889110›Full record

ArticleMicroorganisms2022

Characterization and Comparison of Ocular Surface Microbiome in Newborns.

Francesco Petrillo, Arianna Petrillo, Maddalena Marrapodi, Carlo Capristo, Maria Francesca Gicchino, Paolo Montaldo, Elisabetta Caredda, Michele Reibaldi, Lara M V Boatti, Federica Dell'Annunziata and 2 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  8. Article
  9. Dual Role ofMicroorganisms · 2024
    Article
  10. Article
  11. Characterization of Gut Microbiota Composition in Type 2 Diabetes Patients: A Population-Based Study.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Francesco PetrilloDepartment of Surgical Sciences, Eye Clinic Section, University of Turin, 10124 Turin, Italy.ORCID 0000-0003-0446-2846
Arianna PetrilloPediatric Unit, Fondazione IRCCS "Ca' Granda-Ospedale Maggiore-Policlinico", 20122 Milan, Italy.
Maddalena MarrapodiDepartment of Woman, Child and General and Specialist Surgery, University of Campania "Luigi Vanvitelli", 80138 Napoli, Italy.ORCID 0000-0002-9494-6942
Carlo CapristoDepartment of Neonatology, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Maria Francesca GicchinoDepartment of Woman, Child and General and Specialist Surgery, University of Campania "Luigi Vanvitelli", 80138 Napoli, Italy.
Paolo MontaldoDepartment of Neonatology, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Elisabetta CareddaDepartment of Neonatology, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Michele ReibaldiDepartment of Surgical Sciences, Eye Clinic Section, University of Turin, 10124 Turin, Italy.ORCID 0000-0003-1368-6729
Lara M V BoattiArrow Diagnostics, 16152 Genoa, Italy.
Federica Dell'AnnunziataDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-1654-8500
Veronica FollieroDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-7406-9882
Marilena GaldieroDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-0174-0209
University of Campania "Luigi Vanvitelli" · ITUniversity of Turin · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ocular microbiome is of fundamental importance for immune eye homeostasis, and its alteration would lead to an impairment of ocular functionality. Little evidence is reported on the composition of the ocular microbiota of term infants and on the impact of antibiotic prophylaxis.

methodsA total of 20 conjunctival swabs were collected from newborns at birth and after antibiotic treatment. Samples were subjected to 16S rRNA sequencing via system MiSeq Illumina. The data were processed with the MicrobAT software and statistical analysis were performed using two-way ANOVA.

resultsAntibiotic prophylaxis with gentamicin altered the composition of the microbiota. In detail, a 1.5- and 2.01-fold reduction was recorded for

conclusionsAntibiotic prophylaxis altered the ocular microbiota whose understanding could avoid adverse effects on eye health.

Indexed as

16S rRNA sequencingbacterianewbornocular surface microbiota

Identifiers

PMID35889110
PMCPMC9320102
OpenAlexW4285006893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.