ArticleMetabolites2022
Renal Sinus Fat Is Expanded in Patients with Obesity and/or Hypertension and Reduced by Bariatric Surgery Associated with Hypertension Remission.
Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 36 citations in OpenAlex.
- Trial
- Integrating kidney imaging for risk prediction, therapeutic monitoring, and prognostication across the kidney disease spectrum: a review of emerging evidence.Clinical kidney journal · 2026Review
- Waist-to-height ratio as a non-invasive marker of renal sinus fat: a MRI-based cohort study.International journal of obesity (2005) · 2026Article
- Perirenal fat: a missing link between mineralocorticoid receptor activation and cardiovascular-kidney-metabolic syndrome in primary aldosteronism.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- The Association Between the Decrease of Perirenal Fat and Hypertension Following Sleeve Gastrectomy: A Single-Center 1-Year Follow-Up Cohort Study.Obesity surgery · 2025Article
- How to individualize renoprotective therapy in obese patients with chronic kidney disease: a commentary by the Diabesity Working Group of the ERA.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Review
- Opportunistic Detection of Chronic Kidney Disease Using CT-Based Measurements of Kidney Volume and Perirenal Fat.Journal of clinical medicine · 2025Article
- Renal Fat Accumulation Assessed by MRI or CT and Its Association with Clinical and Metabolic Disorders: A Systematic Imaging Review.Journal of clinical medicine · 2025Review
- Preliminary quantitative analysis of renal sinus fat dysfunction in T2DM patients using MRI fat fraction and R2* mapping.Frontiers in endocrinology · 2025Article
- Renal fat deposition measured on dixon-based MRI is significantly associated with early kidney damage in obesity.Abdominal radiology (New York) · 2024Article
- Obesity and the kidney: mechanistic links and therapeutic advances.Nature reviews. Endocrinology · 2024Review
- Obesity Is Associated with Fatty Liver and Fat Changes in the Kidneys in Humans as Assessed by MRI.Nutrients · 2024Article
- Does the Location of Fat Accumulation Affect the Degree of Aortic and Renal Arterial Calcification?Biomedicines · 2024Article
- Are we ready for an adipocentric approach in people living with type 2 diabetes and chronic kidney disease?Clinical kidney journal · 2024Review
- Associations of renal sinus fat with metabolic parameters, abdominal visceral adipose tissue, metabolic syndrome, fructose intake, and blood pressure control in obese individuals with hypertension: a cross-sectional study.Journal of nutritional science · 2024Article
- Mechanisms and treatment of obesity-related hypertension-Part 1: Mechanisms.Clinical kidney journal · 2024Review
- Perirenal fat thickness contributes to the estimated 10-year risk of cardiovascular disease and atherosclerotic cardiovascular disease in type 2 diabetes mellitus.Frontiers in endocrinology · 2024Article
- The impact of weight loss on renal function in individuals with obesity and type 2 diabetes: a comprehensive review.Frontiers in endocrinology · 2024Review
- Weight Loss Following Bariatric Surgery in People with or without Metabolic Syndrome: A 5-Year Observational Comparative Study.Journal of clinical medicine · 2024Article
- Renal Perfusion, Oxygenation and Metabolism: The Role of Imaging.Journal of clinical medicine · 2023Review
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
Abstract
Renal sinus fat is a fat depot at the renal hilum. Because of its location around the renal artery, vein, and lymphatic vessels, an expanded renal sinus fat mass may have hemodynamic and renal implications. We studied whether renal sinus fat area (RSF) associates with hypertension and whether following bariatric surgery a decrease in RSF associates with improvement of hypertension. A total of 74 severely obese and 46 lean controls were studied with whole-body magnetic resonance imaging (MRI). A total of 42 obese subjects were re-studied six months after bariatric surgery. RSF was assessed by two independent researchers using sliceOmatic. Glomerular filtration rate (eGFR) was estimated according to the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration). Patients with obesity accumulated more RSF compared to lean controls (2.3 [1.7-3.1] vs. 1.8 [1.4-2.5] cm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.