ReviewMedicina (Kaunas, Lithuania)2022
Surgical Treatment and Rehabilitation Strategies for Upper and Lower Extremity Lymphedema: A Comprehensive Review.
Review in Medicina (Kaunas, Lithuania), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06069908 (The Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Edema, Grip Strength, Dexterity and Quality of Life in Upper Extremity Lymphedema), which is not on this map. Cited by 42 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Edema, Grip Strength, Dexterity and Quality of Life in Upper Extremity Lymphedema
Who cites it
42 citing papers in PubMed, 4 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Interventions to improve the psychosocial outcomes of individuals with lymphedema: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Efficacy of vascularized lymph node transfer for lower extremity lymphedema: A systematic review and meta-analysis of 395 patients from 25 peer-reviewed studies.Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 2026Pooled it
- Efficacy of Immediate Lymphatic Reconstruction in Prevention of Breast Cancer-Related Lymphedema: A Systematic Review and Meta-Analysis.Microsurgery · 2025Pooled it
- Efficacy of kinesio taping on upper limb volume reduction in patients with breast cancer-related lymphedema: a systematic review of randomized controlled trials.European journal of physical and rehabilitation medicine · 2023Pooled it
- Cell-Free Adipose Liquid Extract Combined with Vascularized Lymph Node Transfer for Treating Lymphedema: Implications for Human Therapy.Tissue engineering and regenerative medicine · 2026Article
- Intralesional Bleomycin for Genital Lymphedema-Associated Lymphatic Malformations and Lymphorrhea.Aesthetic plastic surgery · 2026Article
- Social determinants drive lymphedema severity and treatment adherence: evidence from a three-year retrospective cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Finite Element Modeling of Lower Limb Lymphedema: Influence of Limb Morphology and Compression Garment Classes on Internal Pressure Distribution.Annals of biomedical engineering · 2026Article
- Kinesio Taping as an Adjunctive Nursing Intervention for Lower Extremity Edema in ICU Patients: A Case Series.Reports (MDPI) · 2026Article
- Reconstructing cerebral lymphatic clearance: an emerging target in the Alzheimer's disease therapeutic pipeline.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- The Role of Internal Medicine or Hospitalist Co-Management in Surgical Specialties: Implications for Adult and Elderly Plastic Surgery Patients.Medicina (Kaunas, Lithuania) · 2026Article
- Therapeutic potential and mechanisms of rehabilitation interventions in preventing cancer metastasis.Frontiers in oncology · 2026Review
- Technology-enhanced compression and AI-integrated lymphedema care: a narrative review.Irish journal of medical science · 2025Review
- Home self-management experience of gynaecological tumour patients with lower limb lymphoedema: a qualitative study.Primary health care research & development · 2025Article
- Usefulness of Four-Point Dermal-Injection Lymphatic Scintigraphy for Lower-Limb Lymphedema.Cureus · 2025Article
- Correspondence to "Online Information on Lymphedema: Systematic Review of the Quality of Online Patient Resources".Journal of cancer education : the official journal of the American Association for Cancer Education · 2025Article
- Surgical Treatment, Rehabilitative Approaches and Functioning Assessment for Patients Affected by Breast Cancer-Related Lymphedema: A Comprehensive Review.Medicina (Kaunas, Lithuania) · 2025Review
- Effectiveness of Kinesio Taping for Lymphedema in the Post-Mastectomy Patient: A Systematic Review of Randomized Controlled Trials.Journal of clinical medicine · 2025Review
- Prevalence of lower extremity edema following inguinal lymphadenectomy: A systematic review and meta-analysis.JPRAS open · 2025Review
- Letter on: "Meta-analysis of the Oncological Safety of Autologous Fat Grafting After Breast Cancer on Basic Science and Clinical Studies".Aesthetic plastic surgery · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lymphedema is a chronic disabling condition affecting a growing number of patients worldwide. Although lymphedema is not life-threatening, several reports underlined detrimental consequences in terms of distress, pain, functional impairment, and infections with a relevant decrease in quality of life. Currently, there is no cure, and the therapeutic management of this condition aims at slowing down the disease progression and preventing secondary complications. Early diagnosis is paramount to enhance the effects of rehabilitation or surgical treatments. On the other hand, a multidisciplinary treatment should be truly integrated, the combination of microsurgical and reductive procedures should be considered a valid strategy to manage extremity lymphedema, and rehabilitation should be considered the cornerstone of the multidisciplinary treatment not only for patients not suitable for surgical interventions but also before and after surgical procedures. Therefore, a specialized management of Plastic Reconstructive Surgeons and Physical and Rehabilitative Medicine physicians should be mandatory to address patients' needs and optimize the treatment of this disabling and detrimental condition. Therefore, the aim of this review was to characterize the comprehensive management of lymphedema, providing a broad overview of the potential therapy available in the current literature to optimize the comprehensive management of lymphedema and minimize complications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.