Evidence map›Paper›PMID 35888656›Full record

ArticleMedicina (Kaunas, Lithuania)2022

Surgical Treatment Following Failed Medical Treatment of an Interstitial Pregnancy.

Stefano Restaino, Elena De Gennaro, Stefano Floris, Guglielmo Stabile, Giulia Zinicola, Felice Sorrentino, Giuseppe Vizzielli, Lorenza Driul

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Stefano RestainoObstetrics and Gynecology Unit, Department of Obstetrics, Gynecology and Pediatrics, Department of Medical Area DAME, Udine University Hospital, 33100 Udine, Italy.ORCID 0000-0002-7848-0329
Elena De GennaroClinic of Obstetrics and Gynecology, Department of Medical Area (DAME), Hospital of Udine, University of Udine, 33100 Udine, Italy.ORCID 0000-0002-9190-0578
Stefano FlorisObstetrics and Gynecology Unit, Department of Obstetrics, Gynecology and Pediatrics, Department of Medical Area DAME, Udine University Hospital, 33100 Udine, Italy.
Guglielmo StabileInstitute for Maternal and Child Health IRCCS "Burlo Garofolo", 34100 Trieste, Italy.ORCID 0000-0001-9266-3896
Giulia ZinicolaDepartment of Medicine, Surgery and Health Sciences, University of Trieste, 34100 Trieste, Italy.
Felice SorrentinoDepartment of Medical and Surgical Sciences, University of Foggia, 71100 Foggia, Italy.ORCID 0000-0003-3993-2895
Giuseppe VizzielliClinic of Obstetrics and Gynecology, Department of Medical Area (DAME), Hospital of Udine, University of Udine, 33100 Udine, Italy.ORCID 0000-0002-2424-2691
Lorenza DriulClinic of Obstetrics and Gynecology, Department of Medical Area (DAME), Hospital of Udine, University of Udine, 33100 Udine, Italy.
University of Udine · ITIRCCS Materno Infantile Burlo Garofolo · ITUniversity of Foggia · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interstitial pregnancy (IP) is a type of ectopic pregnancy in which the embryo implants in the interstitial part of the Fallopian tube. It accounts for 2% of all ectopic pregnancies. Signs and symptoms appear later than the other forms of ectopic pregnancies because of its peculiar location. The gold standard for its diagnosis is transvaginal ultrasound. The treatment can be medical or surgical. Medical treatment is based on the systemic or local injection of methotrexate (MTX); a dose of mifepristone can be added with a reported 85-90% success rate. The surgical option is laparoscopic unilateral cornuostomy or unilateral salpingectomy. The therapeutic choice is based on symptoms, serum β-human chorionic gonadotropin (β-hCG) values, and sonographic features. Furthermore, the patient's fertility perspectives should be considered. We report a case of IP in a Caucasian woman of 29 years old, with a previous salpingectomy for ectopic pregnancy medically treated by a double dose of intramuscular MTX 50 mg/m

Indexed as

Pregnancy, InterstitialAdultChorionic Gonadotropin, beta Subunit, HumanFallopian TubesFemaleHumansMethotrexateMifepristonePregnancyChorionic Gonadotropin, beta Subunit, HumanMethotrexateMifepristoneinterstitial pregnancylaparoscopymedical treatmentmethotrexatemifepristonesalpingectomy

Identifiers

PMID35888656
PMCPMC9316431
OpenAlexW4285733963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.