Evidence map›Paper›PMID 35888622›Full record

ReviewMedicina (Kaunas, Lithuania)2022

The Angiogenic Balance and Its Implications in Cancer and Cardiovascular Diseases: An Overview.

Cătălina Ionescu, Bogdan Oprea, Georgeta Ciobanu, Milena Georgescu, Ramona Bică, Garofiţa-Olivia Mateescu, Fidan Huseynova, Veronique Barragan-Montero

Open access · goldAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. The Multifaceted Role of Mitochondria in Angiogenesis.International journal of molecular sciences · 2025
    Review
  5. Review
  6. Review
  7. Review
  8. Insights into the mechanisms of angiogenesis in hepatoblastoma.Frontiers in cell and developmental biology · 2025
    Review
  9. Review
  10. Could CHBiomedicines · 2024
    Article
  11. Article
  12. Article
  13. Review
  14. The Role and Regulation of Thromboxane AMolecules (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Cătălina IonescuDepartment of Chemistry, Faculty of Sciences, University of Craiova, 107i Calea București, 200144 Craiova, Romania.ORCID 0000-0002-1315-5074
Bogdan OpreaHistology Department, University of Medicine and Pharmacy, 2-4 Petru Rares, 200349 Craiova, Romania.
Georgeta CiobanuDepartment of Chemistry, Faculty of Sciences, University of Craiova, 107i Calea București, 200144 Craiova, Romania.
Milena GeorgescuClinic for Plastic Surgery and Burns, County Emergency Hospital Craiova, 200642 Craiova, Romania.
Ramona BicăGeneral Hospital-"Victor Babes", 281 Mihai Bravu St., Sector III, 030303 Bucharest, Romania.
Garofiţa-Olivia MateescuHistology Department, University of Medicine and Pharmacy, 2-4 Petru Rares, 200349 Craiova, Romania.ORCID 0000-0001-8249-6289
Fidan HuseynovaLBN, University of Montpellier, 34193 Montpellier, France.
Veronique Barragan-MonteroLBN, University of Montpellier, 34193 Montpellier, France.
University of Craiova · ROUniversity of Medicine and Pharmacy of Craiova · ROAzerbaijan National Academy of Sciences · AZUniversité de Montpellier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiogenesis is the process of developing new blood vessels from pre-existing ones. This review summarizes the main features of physiological and pathological angiogenesis and those of angiogenesis activation and inhibition. In healthy adults, angiogenesis is absent apart from its involvement in female reproductive functions and tissue regeneration. Angiogenesis is a complex process regulated by the action of specific activators and inhibitors. In certain diseases, modulating the angiogenic balance can be a therapeutic route, either by inhibiting angiogenesis (for example in the case of tumor angiogenesis), or by trying to activate the process of new blood vessels formation, which is the goal in case of cardiac or peripheral ischemia.

Indexed as

Cardiovascular DiseasesNeoplasmsAngiogenesis InhibitorsFemaleHumansNeovascularization, PathologicAngiogenesis Inhibitorsactivatorsangiogenesiscancercardiovascular diseasesinhibitors

Identifiers

PMID35888622
PMCPMC9316440
OpenAlexW4283827751

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.