Evidence map›Paper›PMID 35888135›Full record

ArticleLife (Basel, Switzerland)2022

Chemical Composition and Toxicity of PM

Aleksey Larionov, Valentin Volobaev, Anton Zverev, Evgeniya Vdovina, Sebastian Bach, Ekaterina Schetnikova, Timofey Leshukov, Konstantin Legoshchin, Galina Eremeeva

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Aleksey LarionovDepartment of Genetics and Fundamental Medicine, Institute of Biology, Ecology and Natural Resources, Kemerovo State University, 6 Krasnaya Street, 650000 Kemerovo, Russia.ORCID 0000-0002-7974-6483
Valentin VolobaevDepartment of Genetics and Fundamental Medicine, Institute of Biology, Ecology and Natural Resources, Kemerovo State University, 6 Krasnaya Street, 650000 Kemerovo, Russia.
Anton ZverevDepartment of Fundamental and Applied Chemistry, Institute of Fundamental Science, Kemerovo State University, 6 Krasnaya Street, 650000 Kemerovo, Russia.ORCID 0000-0002-4139-9973
Evgeniya VdovinaDepartment of Genetics and Fundamental Medicine, Institute of Biology, Ecology and Natural Resources, Kemerovo State University, 6 Krasnaya Street, 650000 Kemerovo, Russia.
Sebastian BachDepartment of Genetics and Fundamental Medicine, Institute of Biology, Ecology and Natural Resources, Kemerovo State University, 6 Krasnaya Street, 650000 Kemerovo, Russia.ORCID 0000-0003-0523-778X
Ekaterina SchetnikovaDepartment of Genetics and Fundamental Medicine, Institute of Biology, Ecology and Natural Resources, Kemerovo State University, 6 Krasnaya Street, 650000 Kemerovo, Russia.
Timofey LeshukovDepartment of Geology and Geography, Institute of Biology, Ecology and Natural Resources, Kemerovo State University, 6 Krasnaya Street, 650000 Kemerovo, Russia.ORCID 0000-0002-5641-702X
Konstantin LegoshchinDepartment of Geology and Geography, Institute of Biology, Ecology and Natural Resources, Kemerovo State University, 6 Krasnaya Street, 650000 Kemerovo, Russia.ORCID 0000-0002-5584-4345
Galina EremeevaDepartment of Fundamental and Applied Chemistry, Institute of Fundamental Science, Kemerovo State University, 6 Krasnaya Street, 650000 Kemerovo, Russia.

Funding

Russian Foundation for Basic Research 19-05-50114
6 · The paper itself

Abstract

Particulate matter (PM) <10 μm in size represents an extremely heterogeneous and variable group of objects that can penetrate the human respiratory tract. The present study aimed to isolate samples of coarse and ultrafine PM at some distance from polluting industries (1−1.5 km from the border of open-cast mines). PM was collected from snow samples which allowed the accumulation of a relatively large amount of ultrafine particles (UFPs) (50−60 mg) from five objects: three open-cast mines, coal power plants, and control territories. The chemical composition of PM was examined using absorption spectroscopy, luminescence spectroscopy, high-performance liquid chromatography, X-ray diffraction (XRD), and X-ray fluorescence (XRF) analyses of solid particle material samples. Toxicity was assessed in human MRC-5 lung fibroblasts after 6 h of in vitro exposure to PM samples. The absorption spectra of all the samples contained a wide non-elementary absorption band with a maximum of 270 nm. This band is usually associated with the absorption of dissolved organic matter (DOM). The X-ray fluorescence spectra of all the studied samples showed intense lines of calcium and potassium and less intense lines of silicon, sulfur, chlorine, and titanium. The proliferation of MRC-5 cells that were exposed to PM0.1 samples was significantly (p < 0.01) lower than that of MRC-5 cells exposed to PM10 at the same concentration, except for PM samples obtained from the control point. PM0.1 samples—even those that were collected from control territories—showed increased genotoxicity (micronucleus, ‱) compared to PM10. The study findings suggest that UFPs deserve special attention as a biological agent, distinct from larger PMs.

Indexed as

air pollutionmicronucleusMRC-5PMPM chemical propertiesUFP

Identifiers

PMID35888135
PMCPMC9323517

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.