Evidence map›Paper›PMID 35888091›Full record

ArticleLife (Basel, Switzerland)2022

Association of Haptoglobin Phenotypes with Outcomes in Patients with Spontaneous Intracerebral Hemorrhage.

Jin Pyeong Jeon, Sung Woo Han, Tae Yeon Kim, Seung Hyuk Lim, Dong Hyuk Youn, Jong Kook Rhim, Jeong Jin Park, Jun Hyong Ahn, Heung Cheol Kim, Jinseo Yang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jin Pyeong JeonDepartment of Neurosurgery, Hallym University College of Medicine, Chuncheon 24253, Korea.
Sung Woo HanInstitute of New Frontier Research, Hallym University College of Medicine, Chuncheon 24253, Korea.
Tae Yeon KimInstitute of New Frontier Research, Hallym University College of Medicine, Chuncheon 24253, Korea.
Seung Hyuk LimInstitute of New Frontier Research, Hallym University College of Medicine, Chuncheon 24253, Korea.
Dong Hyuk YounInstitute of New Frontier Research, Hallym University College of Medicine, Chuncheon 24253, Korea.
Jong Kook RhimDepartment of Neurosurgery, Jeju National University College of Medicine, Jeju 63243, Korea.
Jeong Jin ParkDepartment of Neurology, Konkuk University Medical Center, Seoul 05030, Korea.ORCID 0000-0001-9325-164X
Jun Hyong AhnDepartment of Neurosurgery, Kangwon National University Hospital, Chuncheon 24289, Korea.
Heung Cheol KimDepartment of Radiology, Hallym University College of Medicine, Chuncheon 24253, Korea.
Jinseo YangDepartment of Neurology, Konkuk University Medical Center, Seoul 05030, Korea.
Hallym University · KRKonkuk University Medical Center · KRJeju National University · KRKangwon National University Hospital · KR

Funding

Institute of Marketing and Social Information Technology 2018R1C1B5043503Korea Health Industry Development Institute HR21C0198
6 · The paper itself

Abstract

objectWe aimed to investigate the association of Haptoglobin (Hp) phenotypes with perihematomal edema (PHE) and neurological outcomes after intracerebral hemorrhage (ICH).

methodsThis prospective multicenter study enrolled patients that suffered ICH from March 2017 to February 2020. Hp phenotypes were determined using Western blotting; relative α1 intensity was calculated in patients with Hp2-1. A multivariable logistic regression analysis was then conducted to identify risk factors for increased relative PHE at 96 h and 3-month poor outcomes.

resultsIn total, 120 patients were ultimately enrolled: Hp1-1 (n = 15, 12.5%); Hp2-1 (n = 51, 42.5%); and Hp2-2 (n = 54, 45.0%). Hp phenotype was significantly associated with PHE (

conclusionsICH patients with Hp2-2 exhibited a higher likelihood of increased rPHE than those with Hp1-1. Higher relative α1 intensities were identified to be closely associated with rPHE in patients with Hp2-1.

Indexed as

haptoglobinintracerebral hemorrhageperihematomal edema

Identifiers

PMID35888091
PMCPMC9318044
OpenAlexW4283825175

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.