Evidence map›Paper›PMID 35888052›Full record

ArticleLife (Basel, Switzerland)2022

Demyelination Lesions Do Not Correlate with Clinical Manifestations by Bordetella pertussis Toxin Concentrations.

Maiara Carolina Perussolo, Bassam Felipe Mogharbel, Claudia Sayuri Saçaki, Dilcele Silva Moreira Dziedzic, Seigo Nagashima, Leanderson Franco de Meira, Luiz Cesar Guarita-Souza, Lúcia de Noronha, Katherine Athayde Teixeira de Carvalho

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Maiara Carolina PerussoloAdvanced Therapy and Cellular Biotechnology in Regenerative Medicine Department, The Pelé Pequeno Príncipe Research Institute, Child and Adolescent Health Research & Pequeno Príncipe Faculties, Curitiba 80240-020, PR, Brazil.
Bassam Felipe MogharbelAdvanced Therapy and Cellular Biotechnology in Regenerative Medicine Department, The Pelé Pequeno Príncipe Research Institute, Child and Adolescent Health Research & Pequeno Príncipe Faculties, Curitiba 80240-020, PR, Brazil.ORCID 0000-0002-1338-0693
Claudia Sayuri SaçakiAdvanced Therapy and Cellular Biotechnology in Regenerative Medicine Department, The Pelé Pequeno Príncipe Research Institute, Child and Adolescent Health Research & Pequeno Príncipe Faculties, Curitiba 80240-020, PR, Brazil.
Dilcele Silva Moreira DziedzicAdvanced Therapy and Cellular Biotechnology in Regenerative Medicine Department, The Pelé Pequeno Príncipe Research Institute, Child and Adolescent Health Research & Pequeno Príncipe Faculties, Curitiba 80240-020, PR, Brazil.
Seigo NagashimaLaboratory of Experimental Pathology, Graduate Program of Health Sciences, School of Medicine, Paraná Pontifical Catholic University (PUCPR), Curitiba 80215-901, PR, Brazil.ORCID 0000-0003-0069-3823
Leanderson Franco de MeiraExperimental Laboratory of Institute of Biological and Health Sciences, Paraná Pontifical Catholic University (PUCPR), Curitiba 80215-901, PR, Brazil.
Luiz Cesar Guarita-SouzaExperimental Laboratory of Institute of Biological and Health Sciences, Paraná Pontifical Catholic University (PUCPR), Curitiba 80215-901, PR, Brazil.ORCID 0000-0003-2781-9705
Lúcia de NoronhaLaboratory of Experimental Pathology, Graduate Program of Health Sciences, School of Medicine, Paraná Pontifical Catholic University (PUCPR), Curitiba 80215-901, PR, Brazil.ORCID 0000-0003-0310-7164
Katherine Athayde Teixeira de CarvalhoAdvanced Therapy and Cellular Biotechnology in Regenerative Medicine Department, The Pelé Pequeno Príncipe Research Institute, Child and Adolescent Health Research & Pequeno Príncipe Faculties, Curitiba 80240-020, PR, Brazil.ORCID 0000-0003-4860-2855
Pontifícia Universidade Católica do Paraná · BR

Funding

Coordination for the Improvement of Higher Education Personnel 001
6 · The paper itself

Abstract

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, characterized as an inflammatory demyelinating disease. Given the need for improvements in MS treatment, many studies are mainly conducted through preclinical models such as experimental allergic encephalomyelitis (EAE). This study analyzes the relationships between histopathological and clinical score findings at EAE. Twenty-three female

Indexed as

animal modelBordetella pertussis toxinclinical scoresexperimental allergic encephalomyelitishistopathologicalmultiple sclerosis

Identifiers

PMID35888052
PMCPMC9316486
OpenAlexW4283640485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.