Evidence map›Paper›PMID 35887997›Full record

ArticleJournal of clinical medicine2022

Prognostic Role of Lung Ultrasound in Children with Bronchiolitis: Multicentric Prospective Study.

Laura Gori, Antonella Amendolea, Danilo Buonsenso, Stefano Salvadori, Maria Chiara Supino, Anna Maria Musolino, Paolo Adamoli, Alfina Domenica Coco, Gian Luca Trobia, Carlotta Biagi and 9 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06425107 (Point-of-Care Lung Ultrasound for Prognosis in Critically Ill Infants With Acute Lower Respiratory Tract Infection), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06425107 unknown statusnot on this mapstarted 2024, after this paper: background citation

Point-of-Care Lung Ultrasound for Prognosis in Critically Ill Infants With Acute Lower Respiratory Tract Infection

TypeobservationalSponsorVittore Buzzi Children's HospitalRan2024 to 2025Enrolled100ConditionsBronchiolitis, Noninvasive Ventilation
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 8 institutions in 1 country.

Laura GoriPediatric Unit, Valle del Serchio General Hospital, 55051 Barga, Italy.ORCID 0000-0001-9458-5668
Antonella AmendoleaPediatric Unit, Cecina Civil Hospital, 57023 Cecina, Italy.
Danilo BuonsensoDepartment of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A, Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0001-8567-2639
Stefano SalvadoriInstitute of Clinical Physiology, CNR, 56124 Pisa, Italy.ORCID 0000-0002-1266-3931
Maria Chiara SupinoDepartment of Pediatric Emergency, Bambin Gesù Children's Hospital IRCCS, 00165 Rome, Italy.ORCID 0000-0003-2507-8886
Anna Maria MusolinoDepartment of Pediatric Emergency, Bambin Gesù Children's Hospital IRCCS, 00165 Rome, Italy.
Paolo AdamoliPediatric Unit, Moriggia Pelascini Hospital, Gravedona et Uniti, 22015 Como, Italy.
Alfina Domenica CocoPediatric Unit, Moriggia Pelascini Hospital, Gravedona et Uniti, 22015 Como, Italy.
Gian Luca TrobiaPediatric and Pediatric Emergency Room Unit, Cannizzaro Emergency Hospital, 95126 Catania, Italy.ORCID 0000-0002-6943-4638
Carlotta BiagiPediatric Emergency Unit, Sant'Orsola Hospital IRCCS, 40138 Bologna, Italy.ORCID 0000-0002-9782-6313
Marco LucheriniPediatric Unit, Nottola Hospital, Montepulciano, 53045 Siena, Italy.
Alberto LeonardiPediatric Clinic, Department of Surgical and Biomedical Sciences, University of Perugia, 06132 Perugia, Italy.
Giuseppe LimoliDepartment of Pediatrics, Lodi Hospital, 26900 Lodi, Italy.ORCID 0000-0002-2156-170X
Matteo GiampietriDepartment of Maternal and Child Health, Division of Neonatology and Neonatal Intensive Care Unit, S. Chiara Hospital, University of Pisa, 56100 Pisa, Italy.
Tiziana Virginia SciaccaPediatric and Pediatric Emergency Room Unit, Cannizzaro Emergency Hospital, 95126 Catania, Italy.
Rosa MorelloDepartment of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A, Gemelli IRCCS, 00168 Rome, Italy.
Francesco TursiPneumology Unit, Civil Hospital, Codogno, 26845 Lodi, Italy.
Gino SoldatiDiagnostic and Interventional Ultrasound Unit, Valle del Serchio General Hospital, Castelnuovo Garfagnana, 55032 Lucca, Italy.
Ecobron GroupPediatric Unit and Pediatric Emergency Unit, Azienda Ospedaliera Universitaria Policlinico San Marco, University of Catania, 95121 Catania, Italy.
Agostino Gemelli University Polyclinic · ITBambino Gesù Children's Hospital · ITMoriggia Pelascini Hospital · ITOspedale Cannizzaro · ITIstituto di Fisiologia Clinica · ITOspedale Maggiore di Lodi · ITUniversity of Perugia · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is increasing recognition of the role of lung ultrasound (LUS) to assess bronchiolitis severity in children. However, available studies are limited to small, single-center cohorts. We aimed to assess a qualitative and quantitative LUS protocol to evaluate the course of bronchiolitis at diagnosis and during follow-up. This is a prospective, multicenter study. Children with bronchiolitis were stratified according to clinical severity and underwent four LUS evaluations at set intervals. LUS was classified according to four models: (1) positive/negative; (2) main LUS pattern (normal/interstitial/consolidative/mixed) (3) LUS score; (4) LUS score with cutoff. Two hundred and thirty-three children were enrolled. The baseline LUS was significantly associated with bronchiolitis severity, using both the qualitative (positive/negative LUS p < 0.001; consolidated/normal LUS pattern or mixed/normal LUS p < 0.001) and quantitative models (cutoff score > 9 p < 0.001; LUS mean score p < 0.001). During follow-up, all LUS results according to all LUS models improved (p < 0.001). Better cut off value was declared at a value of >9 points. Conclusions: Our study supports the role of a comprehensive qualitative and quantitative LUS protocol for the identification of severe cases of bronchiolitis and provides data on the evolution of lung aeration during follow-up.

Indexed as

bronchiolitischildrenlung ultrasoundrespiratory syncytial virusultrasound score

Identifiers

PMID35887997
PMCPMC9316238
OpenAlexW4286494061

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.