ArticleJournal of clinical medicine2022
Infective Endocarditis in People Who Inject Drugs: Report from the Italian Registry of Infective Endocarditis.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 9 citations in OpenAlex.
- Tricuspid Valve Infective Endocarditis in People Who Inject Drugs: A Single-Center Retrospective Observational Study of Percutaneous Mechanical Aspiration and a Surgical Approach.Infectious disease reports · 2026Article
- Clinical Spectrum of Infections Among People Who Inject Drugs, With Special Reference to Infective Endocarditis.Cureus · 2025Article
- Article
- Characteristics of Infective Endocarditis in Intravenous Drug Users vs. Non-Users: A Retrospective Study Conducted in Bucharest, Romania.Medicina (Kaunas, Lithuania) · 2025Observational
- Bacterial and fungal infections in persons who inject drugs.Clinical microbiology reviews · 2025Review
- Review
- Infective Endocarditis Presenting As Meningeal Syndrome in an Intravenous Drug User: A Diagnostic Challenge.Cureus · 2025Article
- Epidemiology, Diagnosis, Treatment, and Prognosis of Infective Endocarditis.Journal of clinical medicine · 2023Article
- The Changing Complementary Role of Multimodality Imaging in Clinical Cardiology.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
20 authors at 13 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intravenous drug use is a predisposing condition for infective endocarditis (IE). We report the clinical features of IE, taken from the Italian Registry of IE, in people who inject drugs (PWIDs). The registry prospectively collected epidemiological, clinical, in-hospital, and follow-up data on patients with IE from 17 Italian centers. A total of 677 patients were enrolled, and 61 (9%) were intravenous drug users (IDUs). Most PWIDs were male (78.6%), and aged between 41 and 50 years old (50%). The most frequent comorbidities were HIV (34.4%) and chronic liver disease (32%). Predisposing factors for IE were present in 6.5% of the patients, and 10% had minor valvular abnormalities. IE had occurred previously in 16.4% of the patients, and 50% of them had undergone heart surgery. Overall mortality was 9.8% in IDUs and 20% in patients with recurrent IE. IE in PWIDs mostly affected the native valves (90%). The echocardiographic diagnosis of IE was based on the detection of vegetation in 91.82% of cases.
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Registered trials
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