Evidence map›Paper›PMID 35887831›Full record

ArticleJournal of clinical medicine2022

Impact of COVID-19 on Subclinical Placental Thrombosis and Maternal Thrombotic Factors.

Marie Carbonnel, Camille Daclin, Morgan Tourne, Emmanuel Roux, Mathilde Le-Marchand, Catherine Racowsky, Titouan Kennel, Eric Farfour, Marc Vasse, Jean-Marc Ayoubi

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Marie CarbonnelDepartment of Obstetrics and Gynecology, Hospital Foch, 40, Rue Worth, 92150 Suresnes, France.ORCID 0000-0001-9935-1203
Camille DaclinDepartment of Obstetrics and Gynecology, Hospital Foch, 40, Rue Worth, 92150 Suresnes, France.
Morgan TourneMedical School, University of Versailles, Saint-Quentin-en-Yvelines, 55, Avenue de Paris, 78000 Versailles, France.
Emmanuel RouxDepartment of Clinic Research, Hospital Foch, 40, Rue Worth, 92150 Suresnes, France.
Mathilde Le-MarchandDepartment of Clinic Research, Hospital Foch, 40, Rue Worth, 92150 Suresnes, France.
Catherine RacowskyDepartment of Obstetrics and Gynecology, Hospital Foch, 40, Rue Worth, 92150 Suresnes, France.
Titouan KennelDepartment of Clinic Research, Hospital Foch, 40, Rue Worth, 92150 Suresnes, France.ORCID 0000-0002-2783-2945
Eric FarfourDepartment of Clinical Biology, Hospital Foch, 40, Rue Worth, 92150 Suresnes, France.ORCID 0000-0003-3243-8018
Marc VasseDepartment of Clinical Biology, Hospital Foch, 40, Rue Worth, 92150 Suresnes, France.ORCID 0000-0002-8784-7209
Jean-Marc AyoubiDepartment of Obstetrics and Gynecology, Hospital Foch, 40, Rue Worth, 92150 Suresnes, France.
Hôpital Foch · FRUniversité de Versailles Saint-Quentin-en-Yvelines · FRBrigham and Women's Hospital · USInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the context of the SARS-CoV-2 pandemic, our interest was to evaluate the effect of COVID-19 during pregnancy on placenta and coagulation factors.

methodsa prospective cohort study between January and July 2021 of 55 pregnant women stratified into: Group O, 16 patients with ongoing SARS-CoV-2 infection at delivery; Group R, 21 patients with a history of SARS-CoV-2 infection during pregnancy but who recovered prior to delivery; Group C, 18 control patients with no infection at any time. All women had nasopharyngeal SARS-CoV-2 RT-PCR tests performed within 72 h of delivery. Obstetrical complications were recorded and two physiological inhibitors of coagulation, protein Z (PZ) and dependent protease inhibitor (ZPI), were analyzed in maternal and cord blood. All placentae were analyzed by a pathologist for vascular malperfusion.

resultsNo patient in any group had a severe COVID-19 infection. More obstetrical complications were observed in Group O (O:

conclusionCOVID-19 was associated with more obstetrical complications, but not an increased incidence of placental lesions or PZ and ZPI abnormalities.

Indexed as

COVID-19estradiolplacental vascular pathologypregnancyprotein ZthromboticZPI

Identifiers

PMID35887831
PMCPMC9323982
OpenAlexW4285594803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.