Evidence map›Paper›PMID 35887752›Full record

ReviewJournal of clinical medicine2022

Proximal Median Nerve Compression in the Differential Diagnosis of Carpal Tunnel Syndrome.

Pekka Löppönen, Sina Hulkkonen, Jorma Ryhänen

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Imaging of elbow entrapment neuropathies.Insights into imaging · 2025
    Article
  5. Observational
  6. Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Pekka LöppönenDepartment of Orthopedics and Traumatology, Seinäjoki Central Hospital, FI-60220 Seinäjoki, Finland.ORCID 0000-0002-6347-9229
Sina HulkkonenDepartment of Hand Surgery, Helsinki University Hospital, University of Helsinki, FI-00029 Helsinki, Finland.ORCID 0000-0002-0555-047X
Jorma RyhänenDepartment of Hand Surgery, Helsinki University Hospital, University of Helsinki, FI-00029 Helsinki, Finland.ORCID 0000-0002-4676-2831
University of Helsinki · FISeinäjoki University of Applied Sciences · FI

Funding

Finnish Medical Foundation 5302
6 · The paper itself

Abstract

Carpal tunnel syndrome (CTS) is the most common median nerve compression neuropathy. Its symptoms and clinical presentation are well known. However, symptoms at median nerve distribution can also be caused by a proximal problem. Pronator syndrome (PS) and anterior interosseous nerve syndrome (AINS) with their typical characteristics have been thought to explain proximal median nerve problems. Still, the literature on proximal median nerve compressions (PMNCs) is conflicting, making this classic split too simple. This review clarifies that PMNCs should be understood as a spectrum of mild to severe nerve lesions along a branching median nerve, thus causing variable symptoms. Clear objective findings are not always present, and therefore, diagnosis should be based on a more thorough understanding of anatomy and clinical testing. Treatment should be planned according to each patient's individual situation. To emphasize the complexity of causes and symptoms, PMNC should be named proximal median nerve syndrome.

Indexed as

carpal tunnel syndromemedian nerve entrapmentmedian neuropathyneuralgic amyotrophypronator syndrome

Identifiers

PMID35887752
PMCPMC9317082
OpenAlexW4285007829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.