Evidence map›Paper›PMID 35887711›Full record

ArticleJournal of clinical medicine2022

Cognitive Stimulation as Alternative Treatment to Improve Psychological Disorders in Patients with Mild Cognitive Impairment.

María Del Carmen Carcelén-Fraile, Ana María Llera-DelaTorre, Agustín Aibar-Almazán, Diego Fernando Afanador-Restrepo, Mateo Baena-Marín, Fidel Hita-Contreras, Vânia Brandão-Loureiro, Patricia Alexandra García-Garro, Yolanda Castellote-Caballero

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07549074 (Multicomponent Intervention With Healthy Lifestyle Psychoeducation and Cognitive Stimulation to Improve Cognitive Abilities in Older Adults With Mild Cognitive Impairment-A Double-blind Randomized Control Trial), which is not on this map. Cited by 11 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 4 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07549074 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Multicomponent Intervention With Healthy Lifestyle Psychoeducation and Cognitive Stimulation to Improve Cognitive Abilities in Older Adults With Mild Cognitive Impairment-A Double-blind Randomized Control Trial

TypeinterventionalSponsorCity University of Hong KongRan2026 to 2028Enrolled200ConditionsMild Cognitive Impairment (MCI)ArmsCognitive stimulation, Lifestyle psychoeducation, Sham cognitive stimulation, Sham Lifestyle Psychoeducation
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Clinical Effectiveness of Treatments for Mild Cognitive Impairment in Adults: A Systematic Review.European journal of investigation in health, psychology and education · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

María Del Carmen Carcelén-FraileDepartment of Health Sciences, Faculty of Health Sciences, University of Jaén, 23071 Jaén, Spain.
Ana María Llera-DelaTorreDepartment of Health Sciences, Faculty of Health Sciences, University of Jaén, 23071 Jaén, Spain.
Agustín Aibar-AlmazánDepartment of Health Sciences, Faculty of Health Sciences, University of Jaén, 23071 Jaén, Spain.ORCID 0000-0002-9386-9199
Diego Fernando Afanador-RestrepoFaculty of Health Sciences, University Foundation of the Área Andina, Pereira 660004, Colombia.ORCID 0000-0002-7958-0751
Mateo Baena-MarínFaculty of Health Sciences, University Foundation of the Área Andina, Pereira 660004, Colombia.ORCID 0000-0002-0563-9642
Fidel Hita-ContrerasDepartment of Health Sciences, Faculty of Health Sciences, University of Jaén, 23071 Jaén, Spain.ORCID 0000-0001-7215-5456
Vânia Brandão-LoureiroEscola Superior de Educação, Instituto Politécnico de Beja, 7800-295 Beja, Portugal.ORCID 0000-0003-2458-3004
Patricia Alexandra García-GarroGIP Pedagogy Research Group, Faculty of Distance and Virtual Education, Antonio José Camacho University Institution, Santiago de Cali 760016, Colombia.ORCID 0000-0003-2539-6745
Yolanda Castellote-CaballeroDepartment of Health Sciences, Faculty of Health Sciences, University of Jaén, 23071 Jaén, Spain.ORCID 0000-0002-6233-6787
Universidad de Jaén · ESInstitución Universitaria Antonio José Camacho · COInstituto Politécnico de Beja · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Mild cognitive impairment is becoming one of the most common clinical manifestations affecting older people. For this reason, developing non-pharmacological strategies to help improve or maintain the physical condition of patients with mild dementia has become a priority. Therefore, the objective of this study is to provide evidence about the effects of a cognitive stimulation program on cognitive performance, anxiety, depression, and quality of life in people with mild cognitive impairment (MCI) and aged > 70. (2) Methods: This study is a randomized clinical trial. A total of 72 elderly people with MCI participated: 35 in the control group who did not receive any intervention and 36 in the experimental group who received a cognitive stimulation program for 12 weeks. Cognitive performance, depression, anxiety and health-related quality of life (HRQoL) were measured using the Mini-Mental State Examination (MMSE), the Yesavage Geriatric Depression Scale, the Hamilton Rating Scale, and the SF-12, respectively. (3) Results: In the experimental group, significant results were obtained on cognitive performance, depression, anxiety and general health, emotional role, social functioning, vitality, mental health and mental component summary domains of the SF-12. (4) Conclusions: a cognitive stimulation program of 12 weeks improves cognitive performance, anxiety, depression, and HRQoL in people with MCI aged > 70.

Indexed as

anxietycognitive trainingdepressionmild cognitive impairmentquality of life

Identifiers

PMID35887711
PMCPMC9316027
OpenAlexW4284895659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.