Evidence map›Paper›PMID 35887197›Full record

ArticleInternational journal of molecular sciences2022

Use of OCT Angiography to Diagnose and Manage Atypical Presentations of Macular Telangiectasia Type 2.

John Moir, Shivam V Amin, Saira Khanna, Rahul Komati, Lincoln T Shaw, David Dao, Seenu M Hariprasad, Dimitra Skondra

Open access · goldAbstract readCase Reports
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

John MoirPritzker School of Medicine, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-9585-6028
Shivam V AminDepartment of Ophthalmology and Visual Science, University of Chicago Medical Center, Chicago, IL 60637, USA.
Saira KhannaDepartment of Ophthalmology and Visual Science, University of Chicago Medical Center, Chicago, IL 60637, USA.ORCID 0000-0001-7373-9429
Rahul KomatiDepartment of Ophthalmology and Visual Science, University of Chicago Medical Center, Chicago, IL 60637, USA.ORCID 0000-0002-4524-4653
Lincoln T ShawDepartment of Ophthalmology and Visual Science, University of Chicago Medical Center, Chicago, IL 60637, USA.
David DaoDepartment of Ophthalmology and Visual Science, University of Chicago Medical Center, Chicago, IL 60637, USA.
Seenu M HariprasadDepartment of Ophthalmology and Visual Science, University of Chicago Medical Center, Chicago, IL 60637, USA.
Dimitra SkondraDepartment of Ophthalmology and Visual Science, University of Chicago Medical Center, Chicago, IL 60637, USA.
University of Chicago Medical Center · USUniversity of Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macular telangiectasia Type 2 (MacTel) is a bilateral acquired retinal disease characterized by both vascular changes and atrophy of the retina. The purpose of this case series is to highlight the use of optical coherence tomography angiography (OCTA) as a non-invasive imaging modality to distinguish atypical MacTel from other macular conditions with similar presentations. We performed a retrospective review of patients referred to our academic retinal practice with unconfirmed or misdiagnosed MacTel between July 2017 and July 2021. Patients' OCTA imaging findings were reviewed to guide the appropriate diagnosis and management of atypical MacTel. Fifteen eyes from eight patients were included in this study. Six patients were referred with previous diagnoses of either full-thickness macular hole, lamellar hole, vitreomacular traction (VMT), postoperative cystoid macular edema (CME), or diabetic macular edema (DME). Two patients were referred to us to confirm the diagnosis of MacTel. OCTA revealed telangiectatic vessels in the temporal parafovea of all 15 eyes. OCTA also highlighted previously undiagnosed subretinal neovascularization (SRNV) in seven eyes. OCTA imaging is a valuable imaging modality to distinguish MacTel from other macular conditions, whose treatment courses vary substantially. Due to its ease of use, it holds immense potential in the future as treatments for non-proliferative MacTel emerge.

Indexed as

Diabetes Mellitus, Type 2Diabetic RetinopathyMacular EdemaRetinal TelangiectasisFluorescein AngiographyHumansRetinal VesselsRetrospective StudiesTomography, Optical Coherenceimagingmacular telangiectasiaoptical coherence tomography angiographyretina

Identifiers

PMID35887197
PMCPMC9321649
OpenAlexW4285732531

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.