Evidence map›Paper›PMID 35887126›Full record

ArticleInternational journal of molecular sciences2022

Oxidation Stress as a Mechanism of Aging in Human Erythrocytes: Protective Effect of Quercetin.

Alessia Remigante, Sara Spinelli, Nancy Basile, Daniele Caruso, Giuseppe Falliti, Silvia Dossena, Angela Marino, Rossana Morabito

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Hematopoietic Aging and Leukemia: Mechanistic and Therapeutic Insights.International journal of molecular sciences · 2026
    Review
  5. Food science & nutrition · 2026
    Review
  6. Main events and mechanism of human erythrocyte ageing.Expert reviews in molecular medicine · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Synergistic Effects of a Novel Combination of Natural Compounds Prevent HInternational journal of molecular sciences · 2025
    Article
  16. Review
  17. Review
  18. The Promising Role of Polyphenols in Skin Disorders.Molecules (Basel, Switzerland) · 2024
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Alessia RemiganteDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98122 Messina, Italy.ORCID 0000-0001-9934-293X
Sara SpinelliDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98122 Messina, Italy.
Nancy BasileDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98122 Messina, Italy.
Daniele CarusoComplex Operational Unit of Clinical Pathology, Papardo Hospital, 98158 Messina, Italy.
Giuseppe FallitiComplex Operational Unit of Clinical Pathology, Papardo Hospital, 98158 Messina, Italy.
Silvia DossenaInstitute of Pharmacology and Toxicology, Paracelsus Medical University, 5020 Salzburg, Austria.ORCID 0000-0002-6694-9249
Angela MarinoDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98122 Messina, Italy.ORCID 0000-0002-6827-7327
Rossana MorabitoDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98122 Messina, Italy.ORCID 0000-0003-4904-4963
University of Messina · ITAzienda Ospedaliera Ospedali Riuniti Papardo Piemonte · ITParacelsus Medical University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging is a multi-factorial process developing through a complex net of interactions between biological and cellular mechanisms and it involves oxidative stress (OS) as well as protein glycation. The aim of the present work was to verify the protective role of Quercetin (Q), a polyphenolic flavonoid compound, in a d-Galactose (d-Gal)-induced model of aging in human erythrocytes. The anion-exchange capability through the Band 3 protein (B3p) measured by the rate constant of the SO

Indexed as

Oxidative StressQuercetinAntioxidantsErythrocytesGalactoseGlutathioneGlutathione DisulfideGlycated HemoglobinHumansThiobarbituric Acid Reactive SubstancesAntioxidantsGalactoseGlutathioneGlutathione DisulfideGlycated HemoglobinQuercetinThiobarbituric Acid Reactive Substancesagingband 3 protein functiond-Galactoseglycationoxidative stressquercetin

Identifiers

PMID35887126
PMCPMC9323120
OpenAlexW4286240278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.