Evidence map›Paper›PMID 35887116›Full record

ReviewInternational journal of molecular sciences2022

New Insights into TRP Ion Channels in Stem Cells.

Jing Guo, Chang Shan, Jiao Xu, Mei Li, Jiayu Zhao, Wei Cheng

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Emerging nanoplatforms towards microenvironment-responsive glioma therapy.Medical oncology (Northwood, London, England) · 2025
    Review
  7. Review
  8. Roles of TRPM channels in glioma.Cancer biology & therapy · 2024
    Review
  9. Recent Developments in Ion Channel and Ion-Related Signaling.International journal of molecular sciences · 2023
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jing GuoInstitute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China.
Chang ShanInstitute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China.
Jiao XuInstitute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China.
Mei LiInstitute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China.
Jiayu ZhaoInstitute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China.ORCID 0000-0002-3523-2106
Wei ChengInstitute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China.ORCID 0000-0002-4526-7900
Dalian Medical University · CN

Funding

Scientific research fund of educational department of Liaoning Province LZ2020019
6 · The paper itself

Abstract

Transient receptor potential (TRP) ion channels are cationic permeable proteins located on the plasma membrane. TRPs are cellular sensors for perceiving diverse physical and/or chemical stimuli; thus, serving various critical physiological functions, including chemo-sensation, hearing, homeostasis, mechano-sensation, pain, taste, thermoregulation, vision, and even carcinogenesis. Dysregulated TRPs are found to be linked to many human hereditary diseases. Recent studies indicate that TRP ion channels are not only involved in sensory functions but are also implicated in regulating the biological characteristics of stem cells. In the present review, we summarize the expressions and functions of TRP ion channels in stem cells, including cancer stem cells. It offers an overview of the current understanding of TRP ion channels in stem cells.

Indexed as

Transient Receptor Potential ChannelsCell MembraneHumansPainSensationStem CellsTransient Receptor Potential Channelscalcium influxcell cycleproliferationself-renewalstemnessTRPs

Identifiers

PMID35887116
PMCPMC9318110
OpenAlexW4286239896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.