ReviewInternational journal of molecular sciences2022
Insight and Recent Advances into the Role of Topography on the Cell Differentiation and Proliferation on Biopolymeric Surfaces.
Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Review
- Topographical design principles for osteochondral tissue engineering.Bioactive materials · 2026Review
- From Nature to Innovation: Exploring Natural Biopolymers in 3D Bioprinting for Bone Regeneration.ACS omega · 2026Article
- Micro-cold-forming: a simple, rapid, and inexpensive method for the fabrication of microcavities for 3D cell culture.RSC advances · 2026Article
- Mesoporous Bioactive Glasses: A Review on Structure-Directing-Based Synthesis, Characterization, and Biomedical Applications.Materials (Basel, Switzerland) · 2026Review
- Vibration or Stretch? Distinct Mechanoelectrical Signatures Govern Osteogenic Programming in PVDF.ACS applied materials & interfaces · 2026Article
- Comparison between SBMA and MPC coatings on PEEK surface: stability over time and anti-inflammatory effects in vitro.Scientific reports · 2025Article
- Bicontinuous Interconnected Porous Biomaterials for Tissue Engineering and Regeneration.Small science · 2025Article
- Impact of Polymer Degradation on Cellular Behavior in Tissue Engineering.Bioprinting (Amsterdam, Netherlands) · 2025Article
- Enhancing Bone Scaffold Fabrication: A Comparative Study of Manual Casting and Automated 3D Bioprinting.Annals of biomedical engineering · 2025Article
- Review
- Cellular Signaling at the Nano-Bio Interface: Spotlighting Membrane Curvature.Annual review of physical chemistry · 2025Review
- Research progress in the regulation of endothelial cells and smooth muscle cells using a micro-nanostructure.Biomedical engineering online · 2025Review
- Architectural Design of Biomaterial Scaffolds for Hematopoietic Stem Cell Culture.Biomaterials research · 2025Review
- Surface Deformation of Biocompatible Materials: Recent Advances in Biological Applications.Biomimetics (Basel, Switzerland) · 2024Review
- Carboxymethylated and Sulfated Furcellaran fromPolymers · 2024Article
- Additive and Lithographic Manufacturing of Biomedical Scaffold Structures Using a Versatile Thiol-Ene Photocurable Resin.Polymers · 2024Article
- Tuning the Topography of Dynamic 3D Scaffolds through Functional Protein Wrinkled Coatings.Polymers · 2024Article
- Surface Properties of a Biocompatible Thermoplastic Polyurethane and Its Anti-Adhesive Effect againstJournal of functional biomaterials · 2024Article
- Thermoresponsive Smart Copolymer Coatings Based on P(NIPAM-ACS biomaterials science & engineering · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
It is well known that surface topography plays an important role in cell behavior, including adhesion, migration, orientation, elongation, proliferation and differentiation. Studying these cell functions is essential in order to better understand and control specific characteristics of the cells and thus to enhance their potential in various biomedical applications. This review proposes to investigate the extent to which various surface relief patterns, imprinted in biopolymer films or in polymeric films coated with biopolymers, by utilizing specific lithographic techniques, influence cell behavior and development. We aim to understand how characteristics such as shape, dimension or chemical functionality of surface relief patterns alter the orientation and elongation of cells, and thus, finally make their mark on the cell proliferation and differentiation. We infer that such an insight is a prerequisite for pushing forward the comprehension of the methodologies and technologies used in tissue engineering applications and products, including skin or bone implants and wound or fracture healing.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.