ArticleInternational journal of molecular sciences2022
Screening of Genes Related to Sex Determination and Differentiation in Mandarin Fish (
Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 12 citations in OpenAlex.
- Evolution of a ZW sex determination system in sticklebacks.Science advances · 2026Article
- Sex-Specific Marker Development and Identification of an XY Sex Determination System in the Tire Track Eel (Animals : an open access journal from MDPI · 2026Article
- Chromosome-level genome assembly of the Siniperca obscura.Scientific data · 2026Article
- Intron turnover of slc26a1 and slc26a2 and convergence of intron insertion sites.Scientific reports · 2025Article
- Assembly and analysis of Sinipercidae fish sex chromosomes reveals that a supergene drives sex chromosome origin and turnover.Advanced biotechnology · 2025Article
- The telomere-to-telomere gap-free reference genome and taxonomic reassessment of Siniperca roulei.GigaScience · 2025Article
- Identification of sex-specific markers using genome re-sequencing in the blunt snout bream (Megalobrama amblycephala).BMC genomics · 2024Article
- Molecular Cloning of theGenes · 2024Article
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Authors and funding
10 authors at 3 institutions in 1 country.
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Abstract
Mandarin fish has an XX/XY sex-determination system. The female mandarin fish is typically larger than the male. Sex identification and the discovery of genes related to sex determination in mandarin fish have important theoretical significance in the elucidation of the regulation and evolutionary mechanism of animal reproductive development. In this study, the chromosome-level genome of a female mandarin fish was assembled, and we found that LG24 of the genome was an X chromosome. A total of 61 genes on the X chromosome showed sex-biased expression. Only six gonadal genes (LG24G00426, LG24G003280, LG24G003300, LG24G003730, LG24G004200, and LG24G004770) were expressed in the testes, and the expression of the other gene LG24G003870 isoform 1 in the ovaries was significantly higher than that in the testes (p < 0.01). Five (except LG24G003280 and LG24G003300) of the seven aforementioned genes were expressed at the embryonic development stage, suggesting their involvement in early sex determination. The expression of LG24G004770 (encoding HS6ST 3-B-like) was also significantly higher in female muscles than in male muscles (p < 0.01), indicating other functions related to female growth. ZP3 encoded by LG24G003870 isoform 1 increased the C-terminal transmembrane domain, compared with that encoded by other fish zp3 isoforms, indicating their different functions in sex determination or differentiation. This study provides a foundation for the identification of sex-determining genes in mandarin fish.
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