Evidence map›Paper›PMID 35887026›Full record

ArticleInternational journal of molecular sciences2022

Fusion Tag Design Influences Soluble Recombinant Protein Production in

Christoph Köppl, Nico Lingg, Andreas Fischer, Christina Kröß, Julian Loibl, Wolfgang Buchinger, Rainer Schneider, Alois Jungbauer, Gerald Striedner, Monika Cserjan-Puschmann

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 46 citations in OpenAlex.

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  13. Novel processes to obtain pneumococcal surface proteins for vaccines.Applied microbiology and biotechnology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Christoph KöpplAustrian Centre of Industrial Biotechnology, Muthgasse 18, 1190 Vienna, Austria.ORCID 0000-0001-7653-1498
Nico LinggAustrian Centre of Industrial Biotechnology, Muthgasse 18, 1190 Vienna, Austria.ORCID 0000-0002-3574-6991
Andreas FischerAustrian Centre of Industrial Biotechnology, Muthgasse 18, 1190 Vienna, Austria.
Christina KrößAustrian Centre of Industrial Biotechnology, Muthgasse 18, 1190 Vienna, Austria.ORCID 0000-0001-7549-8454
Julian LoiblAustrian Centre of Industrial Biotechnology, Muthgasse 18, 1190 Vienna, Austria.
Wolfgang BuchingerBiopharma Austria, Process Science, Boehringer Ingelheim Regional Center Vienna GmbH & Co KG, Doktor-Boehringer-Gasse 5-11, 1121 Vienna, Austria.
Rainer SchneiderAustrian Centre of Industrial Biotechnology, Muthgasse 18, 1190 Vienna, Austria.ORCID 0000-0003-3371-6470
Alois JungbauerAustrian Centre of Industrial Biotechnology, Muthgasse 18, 1190 Vienna, Austria.ORCID 0000-0001-8182-7728
Gerald StriednerAustrian Centre of Industrial Biotechnology, Muthgasse 18, 1190 Vienna, Austria.ORCID 0000-0001-8366-5195
Monika Cserjan-PuschmannAustrian Centre of Industrial Biotechnology, Muthgasse 18, 1190 Vienna, Austria.ORCID 0000-0002-9811-9709
Austrian Centre of Industrial Biotechnology (Austria) · ATUniversität Innsbruck · ATBoehringer Ingelheim (Austria) · AT

Funding

Austrian Centre of Industrial Biotechnology (Austria)BMK, BMDW, SFG, Standortagentur Tirol, Government of Lower Austria und Vienna Business Agency in the frame work of COMET-Competence Centers for Excellent Technologies. The COMET-Funding Program is managed by the Austrian Research Promotion Agency FFG.
6 · The paper itself

Abstract

Fusion protein technologies to facilitate soluble expression, detection, or subsequent affinity purification in

Indexed as

Escherichia coliGene FusionHumansRecombinant Fusion ProteinsRecombinant ProteinsSolubilityRecombinant Fusion ProteinsRecombinant Proteinsbacteriophage-derived tagcaspase-2fed-batch cultivationinclusion bodyproteolytic cleavage

Identifiers

PMID35887026
PMCPMC9321918
OpenAlexW4285093300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.