Evidence map›Paper›PMID 35886943›Full record

ReviewInternational journal of molecular sciences2022

Beneficial Effects of Theaflavins on Metabolic Syndrome: From Molecular Evidence to Gut Microbiome.

Meng Shi, Yuting Lu, Junling Wu, Zhibing Zheng, Chenghao Lv, Jianhui Ye, Si Qin, Chaoxi Zeng

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Gut microbiota in insulin resistance: a bibliometric analysis.Journal of diabetes and metabolic disorders · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Meng ShiLaboratory of Food Function and Nutrigenomics, College of Food Science and Technology, Hunan Agricultural University, Changsha 410128, China.
Yuting LuLaboratory of Food Function and Nutrigenomics, College of Food Science and Technology, Hunan Agricultural University, Changsha 410128, China.ORCID 0000-0002-3090-7047
Junling WuLaboratory of Food Function and Nutrigenomics, College of Food Science and Technology, Hunan Agricultural University, Changsha 410128, China.
Zhibing ZhengLaboratory of Food Function and Nutrigenomics, College of Food Science and Technology, Hunan Agricultural University, Changsha 410128, China.
Chenghao LvLaboratory of Food Function and Nutrigenomics, College of Food Science and Technology, Hunan Agricultural University, Changsha 410128, China.
Jianhui YeTea Research Institute, Zhejiang University, Hangzhou 310058, China.
Si QinLaboratory of Food Function and Nutrigenomics, College of Food Science and Technology, Hunan Agricultural University, Changsha 410128, China.ORCID 0000-0002-0788-2099
Chaoxi ZengLaboratory of Food Function and Nutrigenomics, College of Food Science and Technology, Hunan Agricultural University, Changsha 410128, China.

Funding

Hunan Province Innovative Postdoctoral Project 2021RC2080Natural Science Foundation of Hunan Province 2021JJ40246
6 · The paper itself

Abstract

In recent years, many natural foods and herbs rich in phytochemicals have been proposed as health supplements for patients with metabolic syndrome (MetS). Theaflavins (TFs) are a polyphenol hydroxyl substance with the structure of diphenol ketone, and they have the potential to prevent and treat a wide range of MetS. However, the stability and bioavailability of TFs are poor. TFs have the marvelous ability to alleviate MetS through antiobesity and lipid-lowering (AMPK-FoxO3A-MnSOD, PPAR, AMPK, PI3K/Akt), hypoglycemic (IRS-1/Akt/GLUT4, Ca

Indexed as

Gastrointestinal MicrobiomeMetabolic SyndromeAMP-Activated Protein KinasesBiflavonoidsCalcium-Calmodulin-Dependent Protein Kinase KinaseCatechinHumansPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktAMP-Activated Protein KinasesBiflavonoidsCalcium-Calmodulin-Dependent Protein Kinase KinaseCAMKK2 protein, humanCatechinPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-akttheaflavinbioavailabilitygut microbiotamechanismmetabolic syndromeTFs

Identifiers

PMID35886943
PMCPMC9317877

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.