Evidence map›Paper›PMID 35886924›Full record

ArticleInternational journal of molecular sciences2022

A Focal Impact Model of Traumatic Brain Injury in

Sydnee L Spruiell Eldridge, Jonathan F K Teetsel, Ray A Torres, Christina H Ulrich, Vrutant V Shah, Devanshi Singh, Melissa J Zamora, Steven Zamora, Amy K Sater

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Blood-Brain Barrier Disruption and Edema in Xenopus: Methods for Analysis.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  3. The Effects ofNutrients · 2025
    Article
  4. Revisiting the critical roles of reactive microglia in traumatic brain injury.International journal of surgery (London, England) · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Abusive Head Trauma Animal Models: Focus on Biomarkers.International journal of molecular sciences · 2023
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Sydnee L Spruiell EldridgeDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.ORCID 0000-0001-9600-5946
Jonathan F K TeetselDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.
Ray A TorresDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.
Christina H UlrichDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.ORCID 0000-0002-5169-9339
Vrutant V ShahDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.ORCID 0000-0001-5342-6513
Devanshi SinghDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.
Melissa J ZamoraDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.
Steven ZamoraDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.
Amy K SaterDepartment of Biology and Biochemistry, University of Houston, Houston, TX 77204, USA.
University of Houston · USBaker Hughes (United States) · USShriners Hospitals for Children - Houston · USTakara (United States) · USThe University of Texas MD Anderson Cancer Center · USUniversity of North Texas · US

Funding

Olympus FV3000 Confocal Microscope for the Biology and Biochemistry Imaging Core Facility at the University of HoustonS10OD026827 · OD · UNIVERSITY OF HOUSTON · PI LEKVEN, ARNE C · 2020 to 2020
$359k
NIH HHS S10 OD026827Robert J. Kleberg Jr and Helen C. Kleberg Foundation no number
6 · The paper itself

Abstract

Traumatic Brain Injury (TBI) is a global driver of disability, and we currently lack effective therapies to promote neural repair and recovery. TBI is characterized by an initial insult, followed by a secondary injury cascade, including inflammation, excitotoxicity, and glial cellular response. This cascade incorporates molecular mechanisms that represent potential targets of therapeutic intervention. In this study, we investigate the response to focal impact injury to the optic tectum of

Indexed as

AstrocytesBrain Injuries, TraumaticAnimalsDisease Models, AnimalInflammationLarvaMammalsMiceMice, Inbred C57BLMicrogliaNeuroinflammatory DiseasesXenopus laevisastrocytebrain injuryinflammationmicrogliatadpoleTBIXenopus

Identifiers

PMID35886924
PMCPMC9323330
OpenAlexW4284891550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.