Evidence map›Paper›PMID 35886900›Full record

ArticleInternational journal of molecular sciences2022

A Non-Cell-Autonomous Mode of DNA Damage Response in Soma of

Zhangyu Dai, Wenjing Zhang, Mengke Shang, Huangqi Tang, Lijun Wu, Yuejin Wu, Ting Wang, Po Bian

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Zhangyu DaiKey Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China.
Wenjing ZhangKey Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China.
Mengke ShangInstitute of Physical Science and Information Technology, Anhui University, Hefei 230601, China.
Huangqi TangKey Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China.
Lijun WuInstitute of Physical Science and Information Technology, Anhui University, Hefei 230601, China.
Yuejin WuKey Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China.
Ting WangTeaching and Research Section of Nuclear Medicine, School of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China.ORCID 0000-0002-4839-6329
Po BianKey Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China.ORCID 0000-0002-2581-9317
Anhui Medical University · CNAnhui University · CNChinese Academy of Sciences · CNUniversity of Science and Technology of China · CN

Funding

National Natural Science Foundation of China (12075275，12135016the Dean's Fund of Hefei Institute of Physical Science YZJJZX202014the Fund of Innovative Center of Radiation Application KFZC2021010401the Heavy Ion Research Facility in Lanzhou HIR2021PY014the Strategic Priority Research Program of the Chinese Academy of Sciences XDA17010502
6 · The paper itself

Abstract

Life has evolved a mechanism called DNA damage response (DDR) to sense, signal and remove/repair DNA damage, and its deficiency and dysfunction usually lead to genomic instability and development of cancer. The signaling mode of the DDR has been believed to be of cell-autonomy. However, the paradigm is being shifted with in-depth research into model organism

Indexed as

Caenorhabditis elegansDNA RepairAnimalsAtaxia Telangiectasia Mutated ProteinsDNA DamageFemaleGerm CellsNeuronsAtaxia Telangiectasia Mutated ProteinsC. elegansCPR-4DNA damage responseionizing radiationnon-cell-autonomy

Identifiers

PMID35886900
PMCPMC9318560
OpenAlexW4284894797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.