Evidence map›Paper›PMID 35886892›Full record

ArticleInternational journal of molecular sciences2022

Synergistic Antibacterial Activity with Conventional Antibiotics and Mechanism of Action of Shikonin against Methicillin-Resistant

Qian-Qian Li, Hee-Sung Chae, Ok-Hwa Kang, Dong-Yeul Kwon

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Antibacterial potential of danthron, embelin, sanguinarine and shikonin against multidrug-resistant Neisseria gonorrhoeae in vitro.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Biofilm · 2024
    Review
  10. Review
  11. Inhibition of Biofilm Formation inInternational journal of molecular sciences · 2024
    Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Qian-Qian LiDepartment of Oriental Pharmacy, College of Pharmacy and Wonkwang Oriental Medicines Research Institute, Wonkwang University, Iksan 54538, Jeonbuk, Korea.
Hee-Sung ChaeNational Center for Natural Products Research, School of Pharmacy, The University of Mississippi, Oxford, MS 38677, USA.
Ok-Hwa KangDepartment of Oriental Pharmacy, College of Pharmacy and Wonkwang Oriental Medicines Research Institute, Wonkwang University, Iksan 54538, Jeonbuk, Korea.
Dong-Yeul KwonDepartment of Oriental Pharmacy, College of Pharmacy and Wonkwang Oriental Medicines Research Institute, Wonkwang University, Iksan 54538, Jeonbuk, Korea.ORCID 0000-0002-6885-1499
Wonkwang University · KRUniversity of Mississippi · US

Funding

National Research Foundation of Korea 2020R1F1A1054227National Research Foundation of Korea NRF-2021R1I1A1A01058728
6 · The paper itself

Abstract

Methicillin-resistant

Indexed as

Methicillin-Resistant Staphylococcus aureusAnti-Bacterial AgentsDrug SynergismMicrobial Sensitivity TestsNaphthoquinonesStaphylococcus aureusAnti-Bacterial AgentsNaphthoquinonesshikoninantibacterial activityantibiofilm activityMRSAPBP2ashikoninsynergistic effectvirulence factorα-hemolysin

Identifiers

PMID35886892
PMCPMC9322759
OpenAlexW4284894339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.