Polyamine Oxidase Expression Is Downregulated by 17β-Estradiol via Estrogen Receptor 2 in Human MCF-7 Breast Cancer Cells.

Open access · goldAbstract read

In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it

0cells of the map it votes in

6citing papers in PubMed

0.7field-weighted citation impact, top 33% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

Polyamine metabolism and anti-tumor immunity.Frontiers in immunology · 2025
Review
Single-cell expression and immune infiltration analysis of polyamine metabolism in breast cancer.Discover oncology · 2024
Article
The role of polyamine metabolism in cellular function and physiology.American journal of physiology. Cell physiology · 2024
Review
Polyamine Catabolism Revisited: Acetylpolyamine Oxidase Plays a Minor Role due to Low Expression.Cells · 2024
Article
SPARC Is Highly Expressed in Young Skin and Promotes Extracellular Matrix Integrity in Fibroblasts via the TGF-β Signaling Pathway.International journal of molecular sciences · 2023
Article
Expression of Polyamine Oxidase in Fibroblasts Induces MMP-1 and Decreases the Integrity of Extracellular Matrix.International journal of molecular sciences · 2022
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jin Hyung KimDepartment of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.ORCID 0000-0002-2645-4778

Seung-Taek LeeDepartment of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.ORCID 0000-0001-7300-9784

Yonsei University · KR

Funding

National Research Foundation of Korea 2020R1A2C2006556

6 · The paper itself

Abstract

Polyamine levels decrease with menopause; however, little is known about the mechanisms regulated by menopause. In this study, we found that among the genes involved in the polyamine pathway, polyamine oxidase (

Indexed as

Breast NeoplasmsEstrogen Receptor betaOxidoreductases Acting on CH-NH Group DonorsEstradiolEstrogen Receptor alphaFemaleHumansMCF-7 CellsPolyamine OxidasePolyaminesTranscription Factor AP-1EstradiolEstrogen Receptor alphaEstrogen Receptor betaOxidoreductases Acting on CH-NH Group DonorsPolyamine OxidasePolyaminesTranscription Factor AP-117β-estradiol (E2)activator protein 1 (AP-1)estrogen receptor (ESR)polyaminepolyamine oxidase (PAOX)

Identifiers

PMID35886868

DOI10.3390/ijms23147521

PMCPMC9317983

OpenAlexW4284893636

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.