Evidence map›Paper›PMID 35886841›Full record

ArticleInternational journal of molecular sciences2022

The MexJK Multidrug Efflux Pump Is Not Involved in Acquired or Intrinsic Antibiotic Resistance in

Rafael Amieva, Teresa Gil-Gil, José Luis Martínez, Manuel Alcalde-Rico

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Copper homeostasis networks in pseudomonas aeruginosa and the organocopper metabolite fluopsin C.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Trends of Antibiotic Resistance in ESKAPE Pathogens in Mbarara Regional Referral Hospital (2015-2022), South Western, Uganda.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Article
  8. Article
  9. Article
  10. Multidrug efflux pumps ofFrontiers in microbiology · 2024
    Article
  11. Article
  12. Review
  13. Role of Efflux Pumps on Antimicrobial Resistance inInternational journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Rafael AmievaCentro Nacional de Biotecnología, CSIC, Darwin 3, 28049 Madrid, Spain.
Teresa Gil-GilCentro Nacional de Biotecnología, CSIC, Darwin 3, 28049 Madrid, Spain.ORCID 0000-0003-0136-3965
José Luis MartínezCentro Nacional de Biotecnología, CSIC, Darwin 3, 28049 Madrid, Spain.ORCID 0000-0001-8813-7607
Manuel Alcalde-RicoCentro Nacional de Biotecnología, CSIC, Darwin 3, 28049 Madrid, Spain.ORCID 0000-0002-1987-4600
Centro Nacional de Biotecnología · ESPontificia Universidad Católica de Valparaíso · CLUniversidad Complutense de Madrid · ES

Funding

Comunidad de Madrid S2017/BMD-3691Instituto de Salud Carlos III RD16/0016/0011MCIN/AEI /10.13039/501100011033 PID2020-113521RB-I00
6 · The paper itself

Abstract

Multidrug efflux pumps are critical elements in both intrinsic and acquired antibiotic resistance of bacterial populations. Consequently, most studies regarding these protein machineries focus on this specific phenotype. Nevertheless, different works show that efflux pumps participate in other aspects of bacterial physiology too. Herein, we study the

Indexed as

Pseudomonas aeruginosaQuorum SensingAnti-Bacterial AgentsBacterial Outer Membrane ProteinsBacterial ProteinsDrug Resistance, Multiple, BacterialMembrane Transport ProteinsMicrobial Sensitivity TestsAnti-Bacterial AgentsBacterial Outer Membrane ProteinsBacterial ProteinsMembrane Transport ProteinsPA2018 protein, Pseudomonas aeruginosaantibiotic resistanceMexJKPQSPseudomonas aeruginosapyoverdinequorum sensing

Identifiers

PMID35886841
PMCPMC9323910
OpenAlexW4283833017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.