Evidence map›Paper›PMID 35886369›Full record

ArticleInternational journal of environmental research and public health2022

Community Wastewater-Based Surveillance Can Be a Cost-Effective Approach to Track COVID-19 Outbreak in Low-Resource Settings: Feasibility Assessment for Ethiopia Context.

Solomon Ali, Esayas Kebede Gudina, Addisu Gize, Abde Aliy, Birhanemeskel Tegene Adankie, Wondwossen Tsegaye, Gadissa Bedada Hundie, Mahteme Bekele Muleta, Tesfaye Rufael Chibssa, Rediet Belaineh and 4 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Wastewater surveillance for earlier detection of seniors congregate living COVID-19 outbreaks in Peterborough, Ontario.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Solomon AliDepartment of Microbiology, Immunology and Parasitology, St. Paul's Hospital Millennium Medical College, Addis Ababa P.O. Box 1271, Ethiopia.ORCID 0000-0001-5641-8797
Esayas Kebede GudinaDepartment of Internal Medicine, Jimma University, Jimma P.O. Box 378, Ethiopia.ORCID 0000-0002-6264-9695
Addisu GizeDepartment of Microbiology, Immunology and Parasitology, St. Paul's Hospital Millennium Medical College, Addis Ababa P.O. Box 1271, Ethiopia.
Abde AliyNational Animal Health Diagnostic and Investigation Center, Sebeta P.O. Box 04, Ethiopia.ORCID 0000-0002-5906-3343
Birhanemeskel Tegene AdankieDepartment of Microbiology, Immunology and Parasitology, St. Paul's Hospital Millennium Medical College, Addis Ababa P.O. Box 1271, Ethiopia.
Wondwossen TsegayeDepartment of Microbiology, Immunology and Parasitology, St. Paul's Hospital Millennium Medical College, Addis Ababa P.O. Box 1271, Ethiopia.
Gadissa Bedada HundieDepartment of Microbiology, Immunology and Parasitology, St. Paul's Hospital Millennium Medical College, Addis Ababa P.O. Box 1271, Ethiopia.ORCID 0000-0002-5627-9675
Mahteme Bekele MuletaDepartment of Surgery, St. Paul's Hospital Millennium, Medical College, Addis Ababa P.O. Box 1271, Ethiopia.
Tesfaye Rufael ChibssaNational Animal Health Diagnostic and Investigation Center, Sebeta P.O. Box 04, Ethiopia.
Rediet BelainehNational Animal Health Diagnostic and Investigation Center, Sebeta P.O. Box 04, Ethiopia.
Demessa NegessuNational Animal Health Diagnostic and Investigation Center, Sebeta P.O. Box 04, Ethiopia.
Dereje SheguNational Animal Health Diagnostic and Investigation Center, Sebeta P.O. Box 04, Ethiopia.
Guenter FroeschlDivision of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität, 80802 Munich, Germany.ORCID 0000-0003-2743-7555
Andreas WieserDivision of Infectious Diseases and Tropical Medicine, University Hospital, Ludwig-Maximilians-Universität, 80802 Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wastewater surveillance systems have become an important component of COVID-19 outbreak monitoring in high-income settings. However, its use in most low-income settings has not been well-studied. This study assessed the feasibility and utility of wastewater surveillance system to monitor SARS-CoV-2 RNA in Addis Ababa, Ethiopia. The study was conducted at nine Membrane Bio-reactor (MBR) wastewater processing plants. The samples were collected in two separate time series. Wastewater samples and known leftover RT-PCR tested nasopharyngeal swabs were processed using two extraction protocols with different sample conditions. SARS-CoV-2 wastewater RT-PCR testing was conducted using RIDA GENE SARS-CoV-2 RUO protocol for wastewater SARS-CoV-2 RNA testing. Wastewater SARS-CoV-2 RNA RT-PCR protocol adaptation, optimization, and detection were conducted in an Addis Ababa, Ethiopia context. Samples collected during the first time series, when the national COVID-19 case load was low, were all negative. Conversely, samples collected during the second time series were all positive, coinciding with the highest daily reported new cases of COVID-19 in Ethiopia. The wastewater-based SARS-CoV-2 surveillance approach is feasible for Addis Ababa. The COVID-19 wastewater based epidemiological approach can potentially fill the evidence gap in distribution and dynamics of COVID-19 in Ethiopia and other low-income settings.

Indexed as

COVID-19Cost-Benefit AnalysisDisease OutbreaksEthiopiaFeasibility StudiesHumansRNA, ViralSARS-CoV-2WastewaterWastewater-Based Epidemiological MonitoringRNA, ViralWastewaterCOVID-19MBRRT-PCRSARS-CoV-2SPHMMCwastewaterwastewater-based epidemiology

Identifiers

PMID35886369
PMCPMC9319732

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.