SynthesisInternational journal of environmental research and public health2022
Sleep Quality and Aging: A Systematic Review on Healthy Older People, Mild Cognitive Impairment and Alzheimer's Disease.
Synthesis in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
95 citing papers in PubMed, 6 syntheses or guidelines pooled it, 154 citations in OpenAlex.
- Ocular light exposure interventions for sleep, circadian rhythms, rest-activity cycles, mood, and cognitive function in older adults: An Overview of Cochrane and non-Cochrane Systematic Reviews.The Cochrane database of systematic reviews · 2025Pooled it
- The global prevalence of mild cognitive impairment in geriatric population with emphasis on influential factors: a systematic review and meta-analysis.BMC geriatrics · 2025Pooled it
- Effectiveness of Non-Pharmacological Interventions for Sleep Disorders in Enhancing Quality of Life, Cognitive Function, and Sleep Quality in Older Adults with Mild Cognitive Impairment: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Pooled it
- Socially-supported sleep in older adults aged 50 and older: a concept analysis.Frontiers in public health · 2024Pooled it
- The complex burden of determining prevalence rates of mild cognitive impairment: A systematic review.Frontiers in psychiatry · 2022Pooled it
- Prevalence and clinical implications of Rapid eye movement sleep behavior disorder in Alzheimer's disease and Lewy body dementia.GeroScience · 2026Observational
- Associations between multidimensional sleep measures and domain-specific cognitive function across repeated observations in adults aged 55 years and older.GeroScience · 2026Article
- Insomnia symptoms and stress exposure interact in relation to Alzheimer's disease biomarkers.Journal of neurology · 2026Article
- The sleep-wake cycle: molecular mechanisms, disorders, and therapeutic targets in the context of energy metabolism.Signal transduction and targeted therapy · 2026Review
- Association of low sleep efficiency and carotid plaque with cognitive impairment in older adults with chronic diseases: A retrospective cross-sectional study.The Journal of international medical research · 2026Article
- Prospective multidimensional predictors of poor sleep quality in older adults: A cross-national study.Applied psychology. Health and well-being · 2026Article
- Longitudinal relations between sleep quality, psychological distress, and cognitive function among rural older adults: a cross-lagged network analysis.Psychological medicine · 2026Article
- Joint trajectories of brain atrophy, white matter hyperintensities and cognition quantify brain maintenance.Nature communications · 2026Article
- Clowning in care: long-term effectiveness of clown visits on residents' affect, resilience, sleep quality and functionality.BMC geriatrics · 2026Article
- Poor sleep quality is associated with increased mortality in community-dwelling older adults: a retrospective single-center study.Irish journal of medical science · 2026Article
- Association between healthy eating index and sleep quality and duration in older adults: findings from the NeLSA cohort Study, Iran.BMC nutrition · 2026Article
- Coupling of within-person changes in sleep quality and subjective cognition in community-dwelling adults.Aging & mental health · 2026Article
- Impact of Sleep Quality on Cognitive Function in Elderly Patients With Alzheimer's Disease.Actas espanolas de psiquiatria · 2026Article
- Excessive Daytime Sleepiness and Its Associated Factors Among Male Road Transport Workers in Brazil.Journal of sleep research · 2026Article
35 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aging is characterized by changes in the structure and quality of sleep. When the alterations in sleep become substantial, they can generate or accelerate cognitive decline, even in the absence of overt pathology. In fact, impaired sleep represents one of the earliest symptoms of Alzheimer's disease (AD). This systematic review aimed to analyze the studies on sleep quality in aging, also considering mild cognitive impairment (MCI) and AD. The review process was conducted according to the PRISMA statement. A total of 71 studies were included, and the whole sample had a mean age that ranged from 58.3 to 93.7 years (62.8-93.7 healthy participants and 61.8-86.7 pathological populations). Of these selected studies, 33 adopt subjective measurements, 31 adopt objective measures, and 10 studies used both. Pathological aging showed a worse impoverishment of sleep than older adults, in both subjective and objective measurements. The most common aspect compromised in AD and MCI were REM sleep, sleep efficiency, sleep latency, and sleep duration. These results underline that sleep alterations are associated with cognitive impairment. In conclusion, the frequency and severity of sleep disturbance appear to follow the evolution of cognitive impairment. The overall results of objective measures seem more consistent than those highlighted by subjective measurements.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.