Evidence map›Paper›PMID 35885930›Full record

ArticleGenes2022

The Effect of Host miRNAs on Prognosis in COVID-19: miRNA-155 May Promote Severity via Targeting Suppressor of Cytokine Signaling 1 (

Asuman Gedikbasi, Gokhan Adas, Nilgun Isiksacan, Kadriye Kart Yasar, Esra Canbolat Unlu, Rabia Yilmaz, Gulsum Oya Hergunsel, Zafer Cukurova

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Asuman GedikbasiDivision of Medical Genetics, Department of Pediatric Basic Sciences, Institute of Child Health, Istanbul University, 34093 Istanbul, Turkey.ORCID 0000-0001-7121-6077
Gokhan AdasDepartment of Surgery, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, 34180 Istanbul, Turkey.
Nilgun IsiksacanDepartment of Biochemistry, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, 34180 Istanbul, Turkey.
Kadriye Kart YasarDepartment of Infectious Diseases and Clinical Microbiology, Bakırköy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, 34180 Istanbul, Turkey.
Esra Canbolat UnluDepartment of Infectious Diseases and Clinical Microbiology, Bakırköy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, 34180 Istanbul, Turkey.
Rabia YilmazDepartment of Anesthesia and Reanimation, Bakırköy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, 34180 Istanbul, Turkey.
Gulsum Oya HergunselDepartment of Anesthesia and Reanimation, Bakırköy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, 34180 Istanbul, Turkey.
Zafer CukurovaDepartment of Anesthesia and Reanimation, Bakırköy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, 34180 Istanbul, Turkey.
Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi · TRIstanbul University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The epigenetic features contribute to variations in host susceptibility to SARS-CoV-2 infection and severity of symptoms. This study aimed to evaluate the relationship between the relative expression of microRNAs (miRNAs) and the severity of the disease in COVID-19 patients. The miRNA profiles were monitored during the different stages of the disease course using reverse transcription-quantitative polymerase chain reaction (RT-qPCR). The expression levels of the selected 11 miRNAs were measured in the blood samples collected from 73 patients (moderate,

Indexed as

COVID-19MicroRNAsCytokinesHumansPrognosisSARS-CoV-2Suppressor of Cytokine Signaling 1 ProteinCytokinesMicroRNAsMIRN155 microRNA, humanSOCS1 protein, humanSuppressor of Cytokine Signaling 1 ProteinCOVID-19miR-155-5pprognosissuppressor of cytokine signaling 1 (SOCS1)

Identifiers

PMID35885930
PMCPMC9320261
OpenAlexW4283525306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.