Evidence map›Paper›PMID 35885927›Full record

ArticleGenes2022

Internal Introns Promote Backsplicing to Generate Circular RNAs from Spinal Muscular Atrophy Gene.

Diou Luo, Natalia Nikolaevna Singh, Ravindra Narayan Singh

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Translation of circular RNAs.Nucleic acids research · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Diou LuoDepartment of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.
Natalia Nikolaevna SinghDepartment of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.
Ravindra Narayan SinghDepartment of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.ORCID 0000-0001-5399-2662
Iowa State University · US

Funding

Splicing Regulation of Spinal Muscular Atrophy GenesR01NS055925 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SINGH, RAVINDRA N · 2006 to 2023
$5.6M
NINDS NIH HHS R01 NS055925
6 · The paper itself

Abstract

Human

Indexed as

Muscular Atrophy, SpinalNeurodegenerative DiseasesHEK293 CellsHeLa CellsHumansIntronsRNA, CircularSurvival of Motor Neuron 1 ProteinRNA, CircularSurvival of Motor Neuron 1 ProteincircRNAcircular RNASMASMNspinal muscular atrophysurvival motor neuron

Identifiers

PMID35885927
PMCPMC9323214
OpenAlexW4283510965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.