Evidence map›Paper›PMID 35885916›Full record

ArticleGenes2022

Identification of Novel Circular RNAs of the Human Protein Arginine Methyltransferase 1 (

Maria Papatsirou, Marios A Diamantopoulos, Katerina Katsaraki, Dimitris Kletsas, Christos K Kontos, Andreas Scorilas

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Overexpression of CircularInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. High Intratumoral i-tRF-GlyBiomedicines · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Maria PapatsirouDepartment of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece.ORCID 0000-0002-0227-9258
Marios A DiamantopoulosDepartment of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece.
Katerina KatsarakiDepartment of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece.ORCID 0000-0003-2104-5032
Dimitris KletsasLaboratory of Cell Proliferation & Ageing, Institute of Biosciences and Applications, National Centre for Scientific Research "Demokritos", 15341 Aghia Paraskevi, Greece.ORCID 0000-0002-9828-3963
Christos K KontosDepartment of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece.ORCID 0000-0002-9935-8461
Andreas ScorilasDepartment of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece.ORCID 0000-0003-2427-4949
National and Kapodistrian University of Athens · GRNational Centre of Scientific Research "Demokritos" · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNAs (circRNAs) constitute a type of RNA formed through back-splicing. In breast cancer, circRNAs are implicated in tumor onset and progression. Although histone methylation by PRMT1 is largely involved in breast cancer development and metastasis, the effect of circular transcripts deriving from this gene has not been examined. In this study, total RNA was extracted from four breast cancer cell lines and reversely transcribed using random hexamer primers. Next, first- and second-round PCRs were performed using gene-specific divergent primers. Sanger sequencing followed for the determination of the sequence of each novel

Indexed as

Breast NeoplasmsMicroRNAsFemaleHumansProtein-Arginine N-MethyltransferasesRepressor ProteinsRNA, CircularRNA SplicingMicroRNAsPRMT1 protein, humanProtein-Arginine N-MethyltransferasesRepressor ProteinsRNA, Circularalternative splicingback-splice junctionbioinformaticsbreast cancercircRNAsmiRNAsPRMT1RNA-binding proteinsRNA modificationssequencing

Identifiers

PMID35885916
PMCPMC9316507
OpenAlexW4283462078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.