Evidence map›Paper›PMID 35885857›Full record

ArticleHealthcare (Basel, Switzerland)2022

Evaluation of Ibuprofen Use on the Immune System Indicators and Force in Disabled Paralympic Powerlifters of Different Sport Levels.

Felipe J Aidar, Guacira S Fraga, Márcio Getirana-Mota, Anderson Carlos Marçal, Jymmys L Santos, Raphael Fabricio de Souza, Lucio Marques Vieira-Souza, Alexandre Reis Pires Ferreira, Dihogo Gama de Matos, Paulo Francisco de Almeida-Neto and 9 more

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. The Effect of L-Tryptophan Intake on Dynamic Strength in Paralympic Powerlifting.International journal of tryptophan research : IJTR · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 11 institutions in 8 countries.

Felipe J AidarGraduate Program of Physical Education, Federal University of Sergipe (UFS), São Cristovão 49100-000, Brazil.ORCID 0000-0001-7378-4529
Guacira S FragaGraduate Program of Physical Education, Federal University of Sergipe (UFS), São Cristovão 49100-000, Brazil.
Márcio Getirana-MotaGraduate Program of Physical Education, Federal University of Sergipe (UFS), São Cristovão 49100-000, Brazil.ORCID 0000-0002-9022-6251
Anderson Carlos MarçalGraduate Program of Physical Education, Federal University of Sergipe (UFS), São Cristovão 49100-000, Brazil.ORCID 0000-0001-7869-2922
Jymmys L SantosGraduate Program of Physical Education, Federal University of Sergipe (UFS), São Cristovão 49100-000, Brazil.
Raphael Fabricio de SouzaGraduate Program of Physical Education, Federal University of Sergipe (UFS), São Cristovão 49100-000, Brazil.ORCID 0000-0002-3899-6849
Lucio Marques Vieira-SouzaGraduate Program of Physical Education, Federal University of Sergipe (UFS), São Cristovão 49100-000, Brazil.
Alexandre Reis Pires FerreiraCollege of Physical Education and Exercise Science, University of Brasília (UnB), Brasília 70910-900, Brazil.ORCID 0000-0001-9389-1639
Dihogo Gama de MatosCardiovascular & Physiology of Exercise Laboratory, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.ORCID 0000-0002-7394-8527
Paulo Francisco de Almeida-NetoDepartment of Physical Education, Federal University of Rio Grande do Norte, Natal 59064-741, Brazil.ORCID 0000-0002-2860-2260
Nuno Domingos GarridoResearch Center in Sports Sciences, Health Sciences and Human Development (CIDESD), University of Trás-os-Montes e Alto Douro, 5001-801 Vila Real, Portugal.ORCID 0000-0002-8105-7580
Alfonso López Díaz-de-DuranaSports Department, Physical Activity and Sports Faculty-INEF, Universidad Politécnica de Madrid, 28040 Madrid, Spain.
Beat KnechtleInstitute of Primary Care, University of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0002-2412-9103
Breno Guilherme de Araújo Tinoco CabralDepartment of Physical Education, Federal University of Rio Grande do Norte, Natal 59064-741, Brazil.ORCID 0000-0002-9966-9956
Eugenia Murawska-CiałowiczPhysiology and Biochemistry Department, Wroclaw University of Health and Sport Sciences, 51-612 Wroclaw, Poland.ORCID 0000-0001-8512-7278
Hadi NobariDepartment of Exercise Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil 56199-11367, Iran.ORCID 0000-0001-7951-8977
Ana Filipa SilvaEscola Superior de Desporto e Lazer, Instituto Politécnico de Viana do Castelo, Rua Escola Industrial e Comercial de Nun'Álvares, 4900-347 Viana do Castelo, Portugal.ORCID 0000-0002-1772-1272
Filipe Manuel ClementeEscola Superior de Desporto e Lazer, Instituto Politécnico de Viana do Castelo, Rua Escola Industrial e Comercial de Nun'Álvares, 4900-347 Viana do Castelo, Portugal.ORCID 0000-0001-9813-2842
Georgian BadicuDepartment of Physical Education and Special Motricity, Transilvania University of Brasov, 500068 Brasov, Romania.ORCID 0000-0003-4100-8765
Universidade Federal de Sergipe · BRPolytechnic Institute of Viana do Castelo · PTUniversidade Federal do Rio Grande do Norte · BRTransylvania University of Brașov · ROUniversidade de Brasília · BRUniversidad Politécnica de Madrid · ESUniversity of Manitoba · CAUniversity of Mohaghegh Ardabili · IRUniversity of Trás-os-Montes and Alto Douro · PTUniversity of Zurich · CHWroclaw University of Health and Sport Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Paralympic powerlifting (PP) training is typically intense and causes fatigue and alterations in the immune system. Objective: To analyze whether IBU would affect performance and the immune system after training in PP. Methodology: 10 athletes at the national level (NL) and 10 at the regional level (RL) participated in the study, where force and blood indicators were evaluated after training. The study took place over three weeks: (1) familiarization and (2 and 3) comparison between recovery methods, with ibuprofen or placebo (IBU vs. PLA), 800 mg. In the evaluation of the force, the peak torque (PT), fatigue index (FI), and blood immune system biomarkers were analyzed. The training consisted of five sets of five repetitions with 80% of one maximum repetition (5 × 5, 80% 1RM) on the bench press. Results: The PT at the national level using IBU was higher than with PLA (p = 0.007, η2p = 0.347), and the FI in the NL was lower with IBU than with PLA (p = 0.002, η2p = 0.635), and when comparing the use of IBU, the NL showed less fatigue than the regional level (p = 0.004, η2p = 0.414). Leukocytes, with the use of IBU in the NL group, were greater than in the RL (p = 0.001, η2p = 0.329). Neutrophils, in the NL with IBU, were greater than in the RL with IBU and PLA (p = 0.025, η2p = 0.444). Lymphocytes, in NL with IBU were lower than in RL with IBU and PLA (p = 0.001, η2p = 0.491). Monocytes, in the NL with IBU and PLA, were lower than in the RL with IBU (p = 0.049, η2p = 0.344). For hemoglobin, hematocrit, and erythrocyte, the NL with IBU and PLA were higher than the RL with IBU and PLA (p < 0.05). Ammonia, with the use of IBU in the NL, obtained values higher than in the RL (p = 0.007), and with the use of PLA, the NL was higher than the RL (p = 0.038, η2p = 0.570). Conclusion: The training level tends to influence the immune system and, combined with the use of the IBU, it tends to improve recovery and the immune system.

Indexed as

ibuprofenimmune systemmuscle strengthparalympic powerliftingrecovery of function

Identifiers

PMID35885857
PMCPMC9323516
OpenAlexW4285728488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.