Evidence map›Paper›PMID 35885844›Full record

ReviewHealthcare (Basel, Switzerland)2022

Changes in the Epidemiology of Diabetic Retinopathy in Spain: A Systematic Review and Meta-Analysis.

Pedro Romero-Aroca, Maribel López-Galvez, Maria Asuncion Martinez-Brocca, Alicia Pareja-Ríos, Sara Artola, Josep Franch-Nadal, Joan Fernandez-Ballart, José Andonegui, Marc Baget-Bernaldiz

Open access · goldAbstract readReview
In one paragraph

Review in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Visual impairment and blindness in diabetic retinopathy.Medical hypothesis, discovery & innovation ophthalmology journal · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Pedro Romero-ArocaOphthalmic Department, University Hospital Sant Joan, Institut de Investigacio Sanitaries Pere Virgili, Universitat Rovira & Virgili, 43204 Reus, Spain.ORCID 0000-0002-7061-8987
Maribel López-GalvezOphthalmic Department, IOBA, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, Spain.
Maria Asuncion Martinez-BroccaComprehensive Healthcare Plan for Diabetes, Regional Ministry of Health and Families of Andalusia, Government of Andalusia, 14071 Seville, Spain.ORCID 0000-0001-9740-122X
Alicia Pareja-RíosOphthalmic Department, Hospital Universitario de Canarias, Carretera Ofra S/N, 38320 San Cristóbal de La Laguna, Spain.
Sara ArtolaFamily Physiacian, Health Care Center Jose Marva, 28020 Madrid, Spain.
Josep Franch-NadalEAP Raval Sud-Gerencia Territorial Barcelona, Institut Catala de la Salut, IDIAP Jordi Gol/CIBERDEM (IIB Sant Pau), 08006 Barcelona, Spain.ORCID 0000-0002-5175-1555
Joan Fernandez-BallartArea of Preventive Medicine and Public Health, Faculty of Medicine and Health Sciences, Institut d'Investigacions Sanitàries Pere i Virgili, Universitat Rovira i Virgili (URV), 43003 Tarragona, Spain.ORCID 0000-0002-1320-6484
José AndoneguiDepartment of Ophthalmology, Hospital Universitario de Navarra, IdiSNA, Navarra Institute for Health Research, 31009 Pamplona, Spain.ORCID 0000-0002-3109-3743
Marc Baget-BernaldizOphthalmic Department, University Hospital Sant Joan, Institut de Investigacio Sanitaries Pere Virgili, Universitat Rovira & Virgili, 43204 Reus, Spain.
Institut de Recerca Biomèdica Catalunya Sud · ESAndalusian Agency for Healthcare Quality · ESHospital Clínico Universitario de Valladolid · ESHospital Universitario de Canarias · ESInstituto de Salud Carlos III · ESInstitut Universitari d'Investigació en Atenció Primària Jordi Gol · ESMadrid Health Service · ES

Funding

FEDER European Regional Development fund [FEDER],Instituto de Salud Carlos III PI18 / 00169
6 · The paper itself

Abstract

backgroundThe aim of the present study was to determine the prevalence and incidence of diabetic retinopathy (DR) and its changes in the last 20 years in type 2 diabetes mellitus (T2DM) patients in Spain.

methodsA systematic review with a meta-analysis was carried out on the studies published between 2001-2020 on the prevalence and incidence of DR and sight-threatening diabetic retinopathy (STDR) in Spain. The articles included were selected from four databases and publications of the Spanish Ministry of Health and Regional Health Care System (RHCS). The meta-analysis to determine heterogeneity and bias between studies was carried out with the MetaXL 4.0.

resultsSince 2001, we have observed an increase in the detection of patients with DM, and at the same time, screening programs for RD have been launched; thus, we can deduce that the increase in the detection of patients with DM, many of them in the initial phases, far exceeds the increased detection of patients with DR. The prevalence of DR was higher between 2001 and 2008 with values of 28.85%. These values decreased over the following period between 2009 and 2020 with a mean of 15.28%. Similarly the STDR prevalence decrease from 3.67% to 1.92% after 2008. The analysis of the longitudinal studies determined that the annual DR incidence was 3.83%, and the STDR annual incidence was 0.41%.

conclusionIn Spain, for T2DM, the current prevalence of DR is 15.28% and 1.92% forSTDR. The annual incidence of DR is 3.83% and is 0.41% for STDR.

Indexed as

diabetes mellitusdiabetic retinopathy incidencediabetic retinopathy prevalenceepidemiologymeta-analysisscreeningsystematic review

Identifiers

PMID35885844
PMCPMC9320037
OpenAlexW4285732651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.