ReviewHealthcare (Basel, Switzerland)2022
Efficacy of Internet-Based Cognitive Behavioral Therapy for Depression and Anxiety among Global Population during the COVID-19 Pandemic: A Systematic Review and Meta-Analysis of a Randomized Controlled Trial Study.
Review in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07374653 (Online Cognitive Behavioural Therapy for Adolescents With Depression - A Randomized Controlled Trial), which is not on this map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Online Cognitive Behavioural Therapy for Adolescents With Depression - A Randomized Controlled Trial
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Using eHealth to Support Quality of Life and Well-Being in Patients With Lung Cancer: Systematic Review.JMIR cancer · 2025Pooled it
- Guiding future research on psychological interventions in people with COVID-19 and post COVID syndrome and comorbid emotional disorders based on a systematic review.Frontiers in public health · 2023Pooled it
- Trial
- Internet-Based Cognitive Behavioral Therapy for Preventing Postpartum Depressive Symptoms Among Pregnant Individuals With Depression: Multicenter Randomized Controlled Trial in China.Journal of medical Internet research · 2025Trial
- Digital intervention for tokophobia: a randomized controlled trial of internet-based cognitive behavioral therapy on fear of childbirth and self-efficacy among Egyptian pregnant women.BMC pregnancy and childbirth · 2025Trial
- CBT-Intervention for panic disorder in primary care: 5 years follow-up of a cRCT during the Covid-19 pandemic.PloS one · 2023Trial
- Influence of cognitive behavioral therapy-based psychological interventions on psychological well-being and quality of life among laryngeal carcinoma patients.World journal of psychiatry · 2026Article
- Depressive symptoms, violence, and discrimination among transgender women during the COVID-19 pandemic: a cross-sectional study.Revista peruana de medicina experimental y salud publica · 2025Article
- Internet-Delivered Cognitive-Behavioral Therapy (iCBT) for Spanish-Speaking Adults with Prolonged Grief Disorder (PGD): A Randomized Feasibility Trial.Behavioral sciences (Basel, Switzerland) · 2025Article
- What do primary care clinicians and patients think about internet-based computerized cognitive behavioral therapy for depression? A qualitative study from the Veterans Health Administration.Psychological services · 2025Article
- Experiences of Individually Tailored Internet-Based Cognitive Behavioral Therapy During the COVID-19 Pandemic: Qualitative Interview Study.JMIR formative research · 2025Article
- Effects of COVID-19 e-mental health interventions: A systematic review of systematic reviews and meta-analyses.Internet interventions · 2025Article
- Assessing the impact of internet-based cognitive behavioral therapy on sexual dysfunction: A systematic review protocol.PloS one · 2025Article
- Internet-based cognitive behavioral therapy for psychological symptoms during the final phase of the COVID-19 pandemic: a feasibility study.Frontiers in digital health · 2025Article
- Frontiers and hotspots in anxiety disorders: A bibliometric analysis from 2004 to 2024.Heliyon · 2024Article
- Tailored internet-based psychological treatment for psychological problems during the COVID-19 pandemic: A randomized controlled trial.Internet interventions · 2023Article
- Article
- The effectiveness of CBT-based daily supportive text messages in improving female mental health during COVID-19 pandemic: results from the Text4Hope program.Frontiers in global women's health · 2023Article
- Mental health across two years of the COVID-19 pandemic: a 5-wave longitudinal study in Germany.Frontiers in psychiatry · 2023Article
- Unified Protocol for the transdiagnostic treatment of emotional disorders in people with post COVID-19 condition: study protocol for a multiple baseline n-of-1 trial.Frontiers in psychology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Depression and anxiety have become the most common mental health disorders worldwide during the COVID-19 pandemic, and increasing interest in telemedicine has led to the innovation of using internet-based cognitive behavioral therapy (iCBT). Objective: This systematic review and meta-analysis aimed to evaluate the efficacy of iCBT for depression and anxiety among the global population during the COVID-19 pandemic. Methods: A literature search was conducted on PubMed, Scopus, Cochrane, ProQuest, Wiley, and Web of Science using the PRISMA framework, and only randomized controlled trials (RCTs) were included in the study. A critical appraisal was also performed using Cochrane’s Risk of Bias (RoB) 2. The meta-analysis used random-effects models to analyze pooled mean difference (MD) and its p-value. Results: Twelve RCTs were included for qualitative analysis and nine RCTs, which yielded 6778 patients with depression and 6556 patients with anxiety during the COVID-19 pandemic, were included for quantitative analysis. Despite high heterogeneity, all studies had a low risk of bias. Pre- and post-iCBT intervention in the depression forest plot depicts a significant effect (p < 0.00001) with a pooled MD of 4.73 (95% CI: 4.55−4.90), while the pre- and post-iCBT intervention depicts a significant effect (p < 0.00001) with a pooled MD of 4.50 (95% CI: 4.34−4.67). This demonstrates that iCBT was found to significantly decrease depression and anxiety scores in patients during the COVID-19 pandemic. However, substantial heterogeneity was also found (I2 = 93%; p < 0.00001 and I2 = 90%) for the pre-/post-depression and anxiety forest plots, respectively. Conclusions: This meta-analysis comprises an evidence-based result for iCBT to treat depression and anxiety in the COVID-19 population, as indicated by the significantly lower assessment scores. Delivering iCBT in this situation needs to be considered more extensively, as it has promising results and yields the benefits of technological advancement in psychotherapy.
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