Evidence map›Paper›PMID 35885697›Full record

ReviewHealthcare (Basel, Switzerland)2022

Air Pollution and Its Devastating Effects on the Central Nervous System.

Carmen Adella Sîrbu, Ion Stefan, Rodica Dumitru, Marian Mitrica, Aida Mihaela Manole, Titus Mihai Vasile, Constantin Stefani, Aurelian Emil Ranetti

Open access · goldAbstract readReview
In one paragraph

Review in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Orphan Drugs in Neurology-A Narrative Review.Journal of personalized medicine · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Carmen Adella SîrbuDepartment of Neurology, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010242 Bucharest, Romania.ORCID 0000-0002-1982-1066
Ion StefanDepartment of Infectious Diseases, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010242 Bucharest, Romania.
Rodica DumitruDepartment of Neurology, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010242 Bucharest, Romania.
Marian MitricaClinical Neurosciences Department, University of Medicine and Pharmacy "Carol Davila" Bucharest, 050474 Bucharest, Romania.
Aida Mihaela ManoleDepartment of Neurology, Clinical Ambulatory, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010242 Bucharest, Romania.
Titus Mihai VasileClinical Neurosciences Department, University of Medicine and Pharmacy "Carol Davila" Bucharest, 050474 Bucharest, Romania.
Constantin StefaniDepartment of Family Medicine and Clinical Base, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010242 Bucharest, Romania.
Aurelian Emil RanettiDepartment No. 2, University of Medicine and Pharmacy "Carol Davila", 050474 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROTitu Maiorescu University · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Air pollution is a real public health problem, it being one of the five most common causes of mortality in developing countries. However, pollution studies have focused on the cardiovascular and pulmonary systems in recent decades. Recently, researchers have moved towards a new direction, tracing a direct link between pollution and stroke. Stroke has many known risk factors such as smoking, a sedentary lifestyle, and hypertension. Pollution is universally widespread, already a matter of public interest, so that, although intuitive, it is difficult to connect the two. The particles found in the air that we breathe, regardless of their origin, can attack the body in different ways, causing inflammation, and triggering a true cascade of phenomena that end up attacking the central nervous system and other organs. This article tries to explain the series of phenomena that determine the harmful effect of particles present in the air, with an increased focus on the central nervous system and especially on strokes. A deeper understanding of these phenomena helps in guiding future studies and finding viable solutions to protect people at risk.

Indexed as

air pollutionatherosclerosisatrial fibrillationcardiovascular riskneuroinflammationstroke

Identifiers

PMID35885697
PMCPMC9324939
OpenAlexW4283325419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.