Evidence map›Paper›PMID 35885680›Full record

ArticleHealthcare (Basel, Switzerland)2022

Clinical Parameters Affecting the Therapeutic Efficacy of SGLT-2-Comparative Effectiveness and Safety of Dapagliflozin and Empagliflozin in Patients with Type 2 Diabetes.

Irina Claudia Anton, Liliana Mititelu-Tartau, Eliza Gratiela Popa, Mihaela Poroch, Vladimir Poroch, Delia Reurean Pintilei, Gina Eosefina Botnariu

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Irina Claudia AntonDepartment of Pharmacology, Clinical Pharmacology and Algesiology, Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, Universitatii St. 16, 700115 Iasi, Romania.
Liliana Mititelu-TartauDepartment of Pharmacology, Clinical Pharmacology and Algesiology, Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, Universitatii St. 16, 700115 Iasi, Romania.ORCID 0000-0001-7983-3811
Eliza Gratiela PopaDepartment of Pharmaceutical Technology, Faculty of Pharmacy, 'Grigore T. Popa' University of Medicine and Pharmacy, Universitatii St. 16, 700115 Iasi, Romania.
Mihaela PorochDepartment of Family Medicine, Preventive Medicine and Interdisciplinarity, Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, Universitatii St. 16, 700115 Iasi, Romania.
Vladimir Poroch2nd Department of Internal Medicine, Faculty of Medicine, 'Grigore T. Popa' University of Medicine and Pharmacy, Universitatii St. 16, 700115 Iasi, Romania.ORCID 0000-0002-2503-5395
Delia Reurean PintileiDepartment of Diabetes, Nutrition and Metabolic Disease, Consultmed Medical Center, Pacurari St. 70, 700544 Iasi, Romania.
Gina Eosefina BotnariuDepartment of Diabetes, Nutrition and Metabolic Disease, 'Grigore T. Popa' University of Medicine and Pharmacy, Universitatii St. 16, 700115 Iasi, Romania.
Grigore T. Popa University of Medicine and Pharmacy · RO

Funding

Grigore T. Popa University of Medicine and Pharmacy PhD funding
6 · The paper itself

Abstract

(1) Background. We aimed to assess long-term efficacy and safety in inadequately controlled type 2 diabetes (T2DM) of two SGLT-2 inhibitors: empagliflozin (Empa) and dapagliflozin (Dapa), combined with metformin, other oral antidiabetics or insulin, according to the protocols in Romania. (2) Methods. The data of 100 patients treated for T2DM with associated dyslipidemia and/or cardiovascular diseases at the University Hospital and Consultmed Medical Center in Iasi were retrospectively reviewed (2017-2021). In total, 48 patients had received dapagliflozin (10 mg with oral antidiabetics or insulin) and 52 patients received empagliflozin (10 mg /25 mg with oral antidiabetics). (3) Results. In both groups, the lowering of BMI was significant: Dapa group (32.04 ± 4.49 vs. 31.40 ± 4.18 kg/m

Indexed as

antidiabeticsdapagliflozinempagliflozinpatientstype 2 diabetes

Identifiers

PMID35885680
PMCPMC9316348
OpenAlexW4283275733

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.